MetaCap

Evolus (EOLS) vs Talphera (TLPH)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Evolus (EOLS) has outperformed Talphera (TLPH) over the past year, gaining 25.6% versus a loss of 18.2%. Over five years, EOLS leads with a +1.7% price change compared with -94.7% for TLPH. Evolus is the larger company by market cap ($515.2 million vs $56.1 million), about 9.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

EOLS+25.60%TLPH-18.18%
+55%+2%-50%
Oct 8, 20251 yearOct 8, 2026
EOLS+14.37%TLPH-94.55%
+169%+29%-111%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

EOLS versus TLPH key metrics
MetricEOLSTLPH
Share price$7.80$1.08
Market cap$515.19M$56.06M
1-day change+0.78%+2.86%
YTD return+17.29%-5.26%
1-year return+25.60%-18.18%
5-year return+1.69%-94.71%
Forward P/E26.67—
EPS (TTM)$-0.53$-0.26
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$9.31$1.57
52-week low$3.86$0.69
Distance from 52-week high-16.22%-31.21%
Analyst consensusnonenone
Avg. price target upside+92.31%+189.81%
Average volume900.79K238.38K
Shares outstanding66.05M51.91M
Employees35312
SectorHealthcareHealthcare
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & Generic

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Evolus is about 9.2 times larger than Talphera by market value ($515.19M vs $56.06M).
  • EOLS has outperformed TLPH by 43.8 percentage points over the past year.

About Evolus

EOLS stock →

Evolus, Inc., a performance beauty company, delivers products in the cash-pay aesthetic market in the United States, Canada, Europe, and Australia. It offers Jeuveau, a proprietary 900 kilodalton purified botulinum toxin type A formulation for the temporary improvement in the appearance of moderate to severe glabellar lines in adults; and Evolysse, a collection of injectable hyaluronic acid gels, which includes various products, such as mid face, nasolabial folds, lips and eyes.

Healthcare · Drug Manufacturers - Specialty & Generic · 353 employees

About Talphera

TLPH stock →

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. The company's lead product candidate, Niyad, is a lyophilized formulation of nafamostat that acts as a regional anticoagulant for infusion into the extracorporeal circuit.

Healthcare · Drug Manufacturers - Specialty & Generic · 12 employees

EOLS vs TLPH FAQ

Which is bigger, Evolus or Talphera?

Evolus (EOLS) is larger, with a market capitalization of $515.19M compared with $56.06M for Talphera (TLPH).

Which stock has performed better over the past year, EOLS or TLPH?

EOLS returned +25.60% over the past 12 months, compared with -18.18% for TLPH (price return, excluding dividends). Past performance does not predict future results.

Are Evolus and Talphera in the same industry?

Yes. Both are classified in the Drug Manufacturers - Specialty & Generic industry within the Healthcare sector.

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