Establishment Labs (ESTA) vs Inspire Medical Systems (INSP)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Establishment Labs (ESTA) has outperformed Inspire Medical Systems (INSP) over the past year, gaining 51.1% versus a loss of 15.1%. Over five years, ESTA leads with a -21.3% price change compared with -72.8% for INSP. Inspire Medical Systems is the larger company by market cap ($2.00 billion vs $1.84 billion), about 1.1 times the size, while Establishment Labs is growing revenue faster (+27.1% vs +13.6%).
On valuation, Inspire Medical Systems trades at a lower forward P/E (44.8x vs 1030.3x for Establishment Labs). Inspire Medical Systems converts more of its revenue into profit, with a net margin of 15.9% versus -24.2%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ESTA | INSP |
|---|---|---|
| Share price | $61.82 | $69.21 |
| Market cap | $1.84B | $2.00B |
| 1-day change | +1.99% | +3.77% |
| YTD return | -16.84% | -27.69% |
| 1-year return | +51.07% | -15.09% |
| 5-year return | -21.29% | -72.80% |
| P/E ratio (TTM) | — | 15.24 |
| Forward P/E | — | 44.79 |
| EPS (TTM) | $-1.30 | $4.54 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $211.08M | $911.98M |
| Revenue growth (YoY) | +27.14% | +13.60% |
| Net income (latest FY) | $-51.06M | $145.42M |
| Gross margin | 69.32% | 85.39% |
| Operating margin | -18.48% | 5.59% |
| Net margin | -24.19% | 15.95% |
| 52-week high | $97.59 | $147.03 |
| 52-week low | $38.38 | $38.91 |
| Distance from 52-week high | -36.66% | -52.93% |
| Analyst consensus | strong_buy | hold |
| Avg. price target upside | +65.72% | -6.08% |
| Average volume | 427.13K | 798.17K |
| Shares outstanding | 29.80M | 28.91M |
| Employees | 1,004 | 1,333 |
| Sector | Health Care | Health Care |
| Industry | Industrial Specialties | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ESTA has outperformed INSP by 66.2 percentage points over the past year.
- Inspire Medical Systems is more profitable, keeping 15.9 cents of every revenue dollar as net income versus -24.2 cents for Establishment Labs.
- Establishment Labs grew revenue faster in its latest fiscal year (+27.14% vs +13.60%).
About Establishment Labs
ESTA stock →Establishment Labs Holdings Inc., a medical technology company, manufactures and markets medical devices for breast aesthetic and reconstructive plastic surgeries in Europe, the Middle East, Africa, Latin America, Asia, and the United States. The company offers silicone gel-filled breast implants under the Motiva Implants brand.
Health Care · Industrial Specialties · 1,004 employees
About Inspire Medical Systems
INSP stock →Inspire Medical Systems, Inc., a medical technology company, focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA) in the United States and internationally. The company offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for patients with moderate to severe OSA.
Health Care · Medical/Dental Instruments · 1,333 employees
ESTA vs INSP FAQ
Which is bigger, Establishment Labs or Inspire Medical Systems?
Inspire Medical Systems (INSP) is larger, with a market capitalization of $2.00B compared with $1.84B for Establishment Labs (ESTA).
Which stock has performed better over the past year, ESTA or INSP?
ESTA returned +51.07% over the past 12 months, compared with -15.09% for INSP (price return, excluding dividends). Past performance does not predict future results.
Are Establishment Labs and Inspire Medical Systems in the same industry?
Both are in the Health Care sector, but in different industries: Industrial Specialties for Establishment Labs and Medical/Dental Instruments for Inspire Medical Systems.