Establishment Labs (ESTA) vs Penumbra (PEN)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.
Summary
Establishment Labs (ESTA) has outperformed Penumbra (PEN) over the past year, gaining 53.7% versus a gain of 22.2%. Over five years, PEN leads with a +19.3% price change compared with -19.9% for ESTA. Penumbra is the larger company by market cap ($12.58 billion vs $1.84 billion), about 6.8 times the size, while Establishment Labs is growing revenue faster (+27.1% vs +17.5%).
On valuation, Penumbra trades at a lower forward P/E (52.1x vs 1027.8x for Establishment Labs). Penumbra converts more of its revenue into profit, with a net margin of 12.7% versus -24.2%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ESTA | PEN |
|---|---|---|
| Share price | $61.67 | $319.40 |
| Market cap | $1.84B | $12.58B |
| 1-day change | +1.75% | +0.59% |
| YTD return | -15.38% | +2.73% |
| 1-year return | +53.71% | +22.19% |
| 5-year return | -19.91% | +19.29% |
| P/E ratio (TTM) | — | 78.48 |
| Forward P/E | — | 52.09 |
| EPS (TTM) | $-1.30 | $4.07 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $211.08M | $1.40B |
| Revenue growth (YoY) | +27.14% | +17.50% |
| Net income (latest FY) | $-51.06M | $177.69M |
| Gross margin | 69.32% | 67.14% |
| Operating margin | -18.48% | 13.48% |
| Net margin | -24.19% | 12.66% |
| 52-week high | $97.59 | $362.41 |
| 52-week low | $38.55 | $221.26 |
| Distance from 52-week high | -36.81% | -11.87% |
| Analyst consensus | strong_buy | hold |
| Avg. price target upside | +66.11% | +13.21% |
| Average volume | 427.57K | 354.95K |
| Shares outstanding | 29.80M | 39.39M |
| Employees | 1,004 | 4,700 |
| Sector | Health Care | Health Care |
| Industry | Industrial Specialties | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Penumbra is about 6.8 times larger than Establishment Labs by market value ($12.58B vs $1.84B).
- ESTA has outperformed PEN by 31.5 percentage points over the past year.
- Penumbra is more profitable, keeping 12.7 cents of every revenue dollar as net income versus -24.2 cents for Establishment Labs.
- Establishment Labs grew revenue faster in its latest fiscal year (+27.14% vs +17.50%).
About Establishment Labs
ESTA stock →Establishment Labs Holdings Inc., a medical technology company, manufactures and markets medical devices for breast aesthetic and reconstructive plastic surgeries in Europe, the Middle East, Africa, Latin America, Asia, and the United States. The company offers silicone gel-filled breast implants under the Motiva Implants brand.
Health Care · Industrial Specialties · 1,004 employees
About Penumbra
PEN stock →Penumbra, Inc., together with its subsidiaries, designs, develops, manufactures, and markets medical devices in the United States and internationally. It offers computer-assisted vacuum thrombectomy; peripheral thrombectomy products, including the Indigo System for power aspiration of thrombus in the body; Lightning Flash, a mechanical thrombectomy system; Lightning Bolt 7, an arterial thrombectomy system; and CAT RX.
Health Care · Medical/Dental Instruments · 4,700 employees
ESTA vs PEN FAQ
Which is bigger, Establishment Labs or Penumbra?
Penumbra (PEN) is larger, with a market capitalization of $12.58B compared with $1.84B for Establishment Labs (ESTA).
Which stock has performed better over the past year, ESTA or PEN?
ESTA returned +53.71% over the past 12 months, compared with +22.19% for PEN (price return, excluding dividends). Past performance does not predict future results.
Are Establishment Labs and Penumbra in the same industry?
Both are in the Health Care sector, but in different industries: Industrial Specialties for Establishment Labs and Medical/Dental Instruments for Penumbra.