MetaCap

Evommune (EVMN) vs Sionna Therapeutics (SION)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Evommune is the larger company by market cap ($230.1 million vs $223.0 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

EVMN-69.25%SION-85.99%
+63%-15%-94%
Nov 6, 20251 yearOct 7, 2026
EVMN-66.21%SION-86.11%
+79%-7%-94%
Nov 3, 20255 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

EVMN versus SION key metrics
MetricEVMNSION
Share price$6.34$4.94
Market cap$230.09M$223.04M
1-day change+1.93%+2.49%
YTD return-63.67%-88.28%
1-year return—-83.15%
EPS (TTM)$-3.75$-2.16
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$33.20$54.97
52-week low$6.02$4.01
Distance from 52-week high-80.90%-91.01%
Analyst consensusbuyhold
Avg. price target upside+280.60%+325.10%
Average volume697.98K2.19M
Shares outstanding36.29M45.15M
Employees4859
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Evommune

EVMN stock →

Evommune, Inc. operates as a clinical-stage biotechnology company in the United States.

Health Care · Biotechnology: Pharmaceutical Preparations · 48 employees

About Sionna Therapeutics

SION stock →

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-directed CFTR corrector that has completed Phase 1 trial; SION-451, which is nucleotide-binding domain 1 stabilizer in Phase 1 trial; and SION-719, which is nucleotide-binding domain 1 stabilizer in Phase 2a proof-of-concept trial.

Health Care · Biotechnology: Pharmaceutical Preparations · 59 employees

EVMN vs SION FAQ

Which is bigger, Evommune or Sionna Therapeutics?

Evommune (EVMN) is larger, with a market capitalization of $230.09M compared with $223.04M for Sionna Therapeutics (SION).

Are Evommune and Sionna Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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