MetaCap

Exelixis (EXEL) vs Qiagen N.V. (QGEN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Exelixis (EXEL) has outperformed Qiagen N.V. (QGEN) over the past year, gaining 52.7% versus a loss of 4.3%. Over five years, EXEL leads with a +170.5% price change compared with -16.0% for QGEN. Exelixis is the larger company by market cap ($14.62 billion vs $9.20 billion), about 1.6 times the size.

On valuation, Exelixis trades at a lower forward P/E (13.9x vs 17.0x for Qiagen N.V.). Qiagen N.V. pays a dividend yielding 0.82%, while Exelixis does not currently pay one. Exelixis converts more of its revenue into profit, with a net margin of 33.7% versus 20.3%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

EXEL+51.24%QGEN-6.22%
+57%+11%-36%
Oct 8, 20251 yearOct 7, 2026
EXEL+172.99%QGEN-15.02%
+184%+68%-48%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

EXEL versus QGEN key metrics
MetricEXELQGEN
Share price$59.02$44.53
Market cap$14.62B$9.20B
1-day change+0.99%-0.58%
YTD return+34.66%-0.40%
1-year return+52.74%-4.29%
5-year return+170.49%-15.95%
P/E ratio (TTM)18.6222.60
Forward P/E13.9217.04
EPS (TTM)$3.17$1.97
Dividend yield0.00%0.82%
Annual dividend$0.00$0.363
Revenue (latest FY)$2.32B$2.09B
Revenue growth (YoY)+6.98%+5.65%
Net income (latest FY)$782.57M$424.88M
Gross margin96.39%62.18%
Operating margin37.59%22.29%
Net margin33.73%20.33%
52-week high$61.14$57.82
52-week low$33.76$32.53
Distance from 52-week high-3.47%-22.99%
Analyst consensusbuybuy
Avg. price target upside-7.61%+6.15%
Average volume2.34M2.58M
Shares outstanding247.78M206.50M
Employees1,0775,500
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • EXEL has outperformed QGEN by 57.0 percentage points over the past year.
  • Exelixis is more profitable, keeping 33.7 cents of every revenue dollar as net income versus 20.3 cents for Qiagen N.V..

About Exelixis

EXEL stock →

Exelixis, Inc., an oncology company, focuses on the discovery, development, and commercialization of new medicines for difficult-to-treat cancers in the United States. The company offers CABOMETYX tablets for the treatment of patients with advanced renal cell carcinoma who received prior anti-angiogenic therapy; and COMETRIQ capsules for the treatment of progressive and metastatic medullary thyroid cancer.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 1,077 employees

About Qiagen N.V.

QGEN stock →

Qiagen N.V. provides sample to insight solutions that transform biological samples into molecular insights worldwide.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 5,500 employees

EXEL vs QGEN FAQ

Which is bigger, Exelixis or Qiagen N.V.?

Exelixis (EXEL) is larger, with a market capitalization of $14.62B compared with $9.20B for Qiagen N.V. (QGEN).

Which stock has performed better over the past year, EXEL or QGEN?

EXEL returned +52.74% over the past 12 months, compared with -4.29% for QGEN (price return, excluding dividends). Past performance does not predict future results.

Which has the lower P/E ratio, EXEL or QGEN?

EXEL has the lower trailing P/E at 18.6, versus 22.6 for QGEN. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.

Which pays a higher dividend, Exelixis or Qiagen N.V.?

Qiagen N.V. pays a dividend yielding 0.82%, while Exelixis does not currently pay a regular dividend.

Are Exelixis and Qiagen N.V. in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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