MetaCap

Structure Therapeutics (GPCR) vs Precigen (PGEN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Precigen (PGEN) has outperformed Structure Therapeutics (GPCR) over the past year, gaining 136.0% versus a loss of 9.8%. Precigen is the larger company by market cap ($2.72 billion vs $1.83 billion), about 1.5 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

GPCR-9.77%PGEN+136.02%
+242%+110%-22%
Oct 8, 20251 yearOct 8, 2026
GPCR-1.27%PGEN+315.30%
+388%+152%-84%
Jan 30, 20235 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

GPCR versus PGEN key metrics
MetricGPCRPGEN
Share price$25.67$7.60
Market cap$1.83B$2.72B
1-day change-3.79%+0.80%
YTD return-63.09%+81.82%
1-year return-9.77%+136.02%
5-year return—+63.44%
EPS (TTM)$-3.03$-1.04
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$9.68M
Revenue growth (YoY)—+146.73%
Net income (latest FY)—$-250.64M
Operating margin—-1141.13%
Net margin—-2588.21%
52-week high$94.90$8.98
52-week low$25.09$2.99
Distance from 52-week high-72.95%-15.37%
Analyst consensusstrong_buybuy
Avg. price target upside+312.08%+79.61%
Average volume965.00K5.03M
Shares outstanding71.31M358.04M
Employees281160
SectorHealthcareHealthcare
IndustryBiotechnologyBiotechnology

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PGEN has outperformed GPCR by 145.8 percentage points over the past year.

About Structure Therapeutics

GPCR stock →

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, which is in two phase 2 clinical trials for the treatment of obesity, overweight, and related conditions.

Healthcare · Biotechnology · 281 employees

About Precigen

PGEN stock →

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients.

Healthcare · Biotechnology · 160 employees

GPCR vs PGEN FAQ

Which is bigger, Structure Therapeutics or Precigen?

Precigen (PGEN) is larger, with a market capitalization of $2.72B compared with $1.83B for Structure Therapeutics (GPCR).

Which stock has performed better over the past year, GPCR or PGEN?

PGEN returned +136.02% over the past 12 months, compared with -9.77% for GPCR (price return, excluding dividends). Past performance does not predict future results.

Are Structure Therapeutics and Precigen in the same industry?

Yes. Both are classified in the Biotechnology industry within the Healthcare sector.

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