MetaCap

Grifols S.A. (GRFS) vs Kiniksa Pharmaceuticals International (KNSA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Kiniksa Pharmaceuticals International (KNSA) has outperformed Grifols S.A. (GRFS) over the past year, gaining 104.5% versus a loss of 21.8%. Over five years, KNSA leads with a +580.9% price change compared with -47.3% for GRFS. Kiniksa Pharmaceuticals International is the larger company by market cap ($6.06 billion vs $5.02 billion), about 1.2 times the size.

On valuation, Grifols S.A. trades at a lower forward P/E (5.1x vs 48.0x for Kiniksa Pharmaceuticals International).

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

GRFS-21.79%KNSA+104.51%
+119%+43%-34%
Oct 7, 20251 yearOct 7, 2026
GRFS-48.10%KNSA+596.69%
+639%+274%-91%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

GRFS versus KNSA key metrics
MetricGRFSKNSA
Share price$7.38$77.67
Market cap$5.02B$6.06B
1-day change-1.67%-0.37%
YTD return-19.79%+88.99%
1-year return-21.79%+104.51%
5-year return-47.26%+580.87%
P/E ratio (TTM)9.5878.45
Forward P/E5.1148.02
EPS (TTM)$0.77$0.99
Dividend yield1.41%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$677.56M
Revenue growth (YoY)—+60.09%
Net income (latest FY)—$59.01M
Gross margin—88.54%
Operating margin—11.40%
Net margin—8.71%
52-week high$9.90$82.94
52-week low$6.96$35.20
Distance from 52-week high-25.51%-6.35%
Analyst consensusnonestrong_buy
Avg. price target upside+47.39%+26.17%
Average volume580.72K578.96K
Shares outstanding258.22M48.29M
Employees25,258366
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • KNSA has outperformed GRFS by 126.3 percentage points over the past year.
  • Kiniksa Pharmaceuticals International trades at a higher earnings multiple (78.5x vs 9.6x trailing P/E).
  • Grifols S.A. offers a meaningfully higher dividend yield (1.41% vs 0.00%).

About Grifols S.A.

GRFS stock →

Grifols, S.A., together with its subsidiaries, engages in the research, development, production, and marketing of plasma-derived medicines in the United States, Canada, Spain, Europe, and internationally. It operates through four segments: Biopharma, Diagnostic, Bio Supplies, and Others.

Health Care · Biotechnology: Pharmaceutical Preparations · 25,258 employees

About Kiniksa Pharmaceuticals International

KNSA stock →

Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally. The company offers ARCALYST, an interleukin-1alpha and 1beta cytokine trap for the treatment of recurrent pericarditis, a chronic autoinflammatory cardiovascular disease and cardiac sarcoidosis.

Health Care · Biotechnology: Pharmaceutical Preparations · 366 employees

GRFS vs KNSA FAQ

Which is bigger, Grifols S.A. or Kiniksa Pharmaceuticals International?

Kiniksa Pharmaceuticals International (KNSA) is larger, with a market capitalization of $6.06B compared with $5.02B for Grifols S.A. (GRFS).

Which stock has performed better over the past year, GRFS or KNSA?

KNSA returned +104.51% over the past 12 months, compared with -21.79% for GRFS (price return, excluding dividends). Past performance does not predict future results.

Which has the lower P/E ratio, GRFS or KNSA?

GRFS has the lower trailing P/E at 9.6, versus 78.5 for KNSA. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.

Which pays a higher dividend, Grifols S.A. or Kiniksa Pharmaceuticals International?

Grifols S.A. pays a dividend yielding 1.41%, while Kiniksa Pharmaceuticals International does not currently pay a regular dividend.

Are Grifols S.A. and Kiniksa Pharmaceuticals International in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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