MetaCap

Fractyl Health (GUTS) vs SkinHealth Systems (SKIN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

SkinHealth Systems (SKIN) has outperformed Fractyl Health (GUTS) over the past year, losing 66.5% versus a loss of 74.8%. SkinHealth Systems is the larger company by market cap ($74.0 million vs $55.7 million), about 1.3 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

GUTS-74.82%SKIN-66.54%
+76%-3%-82%
Oct 8, 20251 yearOct 8, 2026
GUTS-97.26%SKIN-80.91%
+56%-24%-105%
Jan 29, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

GUTS versus SKIN key metrics
MetricGUTSSKIN
Share price$4.20$0.5689
Market cap$55.71M$74.04M
1-day change-0.71%-3.56%
YTD return-83.98%-59.07%
1-year return-74.82%-66.54%
5-year return—-97.78%
Forward P/E—2.99
EPS (TTM)$-10.56$-0.23
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$29.34$1.74
52-week low$4.14$0.55
Distance from 52-week high-85.69%-67.30%
Analyst consensusstrong_buynone
Avg. price target upside+1338.10%+74.02%
Average volume156.16K489.80K
Shares outstanding13.26M130.14M
Employees100613
SectorHealth CareHealth Care
IndustryMedical/Dental InstrumentsMedical/Dental Instruments

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Fractyl Health

GUTS stock →

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. It develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans.

Health Care · Medical/Dental Instruments · 100 employees

About SkinHealth Systems

SKIN stock →

SkinHealth Systems Inc., a global medical aesthetics company delivering an integrated ecosystem of clinically proven solutions in the Americas, the Asia-Pacific, Europe, the Middle East, Africa, Canada, and Latin America. The company's flagship product is HydraFacial, which enhances the skin to cleanse, extract, and hydrate the skin with proprietary solutions and serums.

Health Care · Medical/Dental Instruments · 613 employees

GUTS vs SKIN FAQ

Which is bigger, Fractyl Health or SkinHealth Systems?

SkinHealth Systems (SKIN) is larger, with a market capitalization of $74.04M compared with $55.71M for Fractyl Health (GUTS).

Which stock has performed better over the past year, GUTS or SKIN?

SKIN returned -66.54% over the past 12 months, compared with -74.82% for GUTS (price return, excluding dividends). Past performance does not predict future results.

Are Fractyl Health and SkinHealth Systems in the same industry?

Yes. Both are classified in the Medical/Dental Instruments industry within the Health Care sector.

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