MetaCap

Gyre Therapeutics (GYRE) vs Obsidian Therapeutics (OBX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Obsidian Therapeutics is the larger company by market cap ($756.1 million vs $716.8 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

GYRE+10.28%OBX-30.06%
+107%+35%-37%
Jul 27, 20261 yearOct 8, 2026
GYRE+17.57%OBX-21.64%
+81%+27%-27%
Jul 27, 20265 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

GYRE versus OBX key metrics
MetricGYREOBX
Share price$6.76$12.24
Market cap$716.79M$756.10M
1-day change-3.98%-7.27%
YTD return-4.25%—
1-year return-7.40%—
5-year return-88.73%—
Forward P/E112.67—
EPS (TTM)$-0.25$-1.63
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$9.42$49.97
52-week low$5.44$12.07
Distance from 52-week high-28.24%-75.51%
Analyst consensusnonestrong_buy
Avg. price target upside+176.18%+218.63%
Average volume105.93K367.35K
Shares outstanding106.03M61.77M
Employees62587
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Gyre Therapeutics

GYRE stock →

Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis. The company offers ETUARY (Pirfenidone), an anti-fibrotic drug approved for the treatment of idiopathic pulmonary fibrosis; and under Phase 3 trials for the treatment of pneumoconiosis.

Health Care · Biotechnology: Pharmaceutical Preparations · 625 employees

About Obsidian Therapeutics

OBX stock →

Obsidian Therapeutics, Inc. operates as a clinical-stage biotechnology company developing engineered cell and gene therapies.

Health Care · Biotechnology: Pharmaceutical Preparations · 87 employees

GYRE vs OBX FAQ

Which is bigger, Gyre Therapeutics or Obsidian Therapeutics?

Obsidian Therapeutics (OBX) is larger, with a market capitalization of $756.10M compared with $716.79M for Gyre Therapeutics (GYRE).

Are Gyre Therapeutics and Obsidian Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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