Halozyme Therapeutics (HALO) vs Moderna (MRNA)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Moderna (MRNA) has outperformed Halozyme Therapeutics (HALO) over the past year, gaining 605.6% versus a gain of 68.5%. Over five years, HALO leads with a +190.9% price change compared with -39.2% for MRNA. Moderna is the larger company by market cap ($89.83 billion vs $12.53 billion), about 7.2 times the size, while Halozyme Therapeutics is growing revenue faster (+37.6% vs -39.9%).
Halozyme Therapeutics converts more of its revenue into profit, with a net margin of 22.7% versus -145.2%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | HALO | MRNA |
|---|---|---|
| Share price | $110.42 | $225.00 |
| Market cap | $12.53B | $89.83B |
| 1-day change | +0.53% | +14.21% |
| YTD return | +63.21% | +568.02% |
| 1-year return | +68.47% | +605.59% |
| 5-year return | +190.89% | -39.24% |
| P/E ratio (TTM) | 32.29 | — |
| Forward P/E | 10.39 | — |
| EPS (TTM) | $3.42 | $-7.98 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $1.40B | $1.94B |
| Revenue growth (YoY) | +37.55% | -39.93% |
| Net income (latest FY) | $316.89M | $-2.82B |
| Gross margin | 83.62% | 55.35% |
| Operating margin | 33.58% | -158.13% |
| Net margin | 22.69% | -145.16% |
| 52-week high | $116.85 | $225.00 |
| 52-week low | $61.23 | $22.28 |
| Distance from 52-week high | -5.50% | 0.00% |
| Analyst consensus | buy | hold |
| Avg. price target upside | -9.84% | -46.22% |
| Average volume | 2.18M | 17.95M |
| Shares outstanding | 113.50M | 399.24M |
| Employees | 423 | 4,700 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Biological Products (No Diagnostic Substances) | Biotechnology: Biological Products (No Diagnostic Substances) |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Moderna is about 7.2 times larger than Halozyme Therapeutics by market value ($89.83B vs $12.53B).
- MRNA has outperformed HALO by 537.1 percentage points over the past year.
- Halozyme Therapeutics is more profitable, keeping 22.7 cents of every revenue dollar as net income versus -145.2 cents for Moderna.
- Halozyme Therapeutics grew revenue faster in its latest fiscal year (+37.55% vs -39.93%).
About Halozyme Therapeutics
HALO stock →Halozyme Therapeutics, Inc., a biopharmaceutical company, researches, develops, and commercializes of proprietary enzymes and devices in the United States, Switzerland, Belgium, Japan, and internationally. The company's products are based on the patented recombinant human hyaluronidase enzyme (rHuPH20) that enables delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 423 employees
About Moderna
MRNA stock →Moderna, Inc., a biotechnology company, provides messenger RNA medicines in the United States, Europe, and internationally. The company's respiratory vaccines include spikevax, mNEXSPIKE, mRESVIA, COVID, RSV, seasonal influenza, combination, and pandemic influenza vaccine; latent vaccines comprise cytomegalovirus, epstein-barr virus, and human immunodeficiency virus vaccines; enteric viruses include norovirus; public health vaccines consist of Zika, Nipah, and Mpox vaccines; and bacterial diseases vaccines, such as lyme vaccines.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 4,700 employees
HALO vs MRNA FAQ
Which is bigger, Halozyme Therapeutics or Moderna?
Moderna (MRNA) is larger, with a market capitalization of $89.83B compared with $12.53B for Halozyme Therapeutics (HALO).
Which stock has performed better over the past year, HALO or MRNA?
MRNA returned +605.59% over the past 12 months, compared with +68.47% for HALO (price return, excluding dividends). Past performance does not predict future results.
Are Halozyme Therapeutics and Moderna in the same industry?
Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.