MetaCap

Werewolf Therapeutics (HOWL) vs SCYNEXIS (SCYX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

SCYNEXIS (SCYX) has outperformed Werewolf Therapeutics (HOWL) over the past year, losing 32.1% versus a loss of 51.6%. Over five years, SCYX leads with a -90.5% price change compared with -94.7% for HOWL. Werewolf Therapeutics is the larger company by market cap ($47.6 million vs $40.7 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

HOWL-51.60%SCYX-32.11%
+49%-20%-90%
Oct 8, 20251 yearOct 8, 2026
HOWL-94.28%SCYX-89.74%
+52%-27%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

HOWL versus SCYX key metrics
MetricHOWLSCYX
Share price$0.9793$4.09
Market cap$47.60M$40.69M
1-day change+7.61%-3.08%
YTD return+43.53%-16.53%
1-year return-51.60%-32.11%
5-year return-94.67%-90.53%
EPS (TTM)$-0.73$-0.89
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$1.85$9.12
52-week low$0.27$3.53
Distance from 52-week high-47.06%-55.15%
Analyst consensusnonestrong_buy
Avg. price target upside+614.80%+788.26%
Average volume6.80M279.10K
Shares outstanding48.60M9.95M
Employees3918
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • SCYX has outperformed HOWL by 19.5 percentage points over the past year.

About Werewolf Therapeutics

HOWL stock →

Werewolf Therapeutics, Inc., a biopharmaceutical company, engages in the development of therapeutics engineered to stimulate the body's immune system for the treatment of cancer and other immune-mediated conditions. The company designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies through its proprietary PREDATOR platform.

Health Care · Biotechnology: Pharmaceutical Preparations · 39 employees

About SCYNEXIS

SCYX stock →

SCYNEXIS, Inc., a biotechnology company, engages in drug development for the treatment and prevention of difficult-to-treat and drug-resistant fungal infections in the United States. The company offers BREXAFEMME for the treatment of patients with vulvovaginal candidiasis and for the reduction in the incidence of recurrence.

Health Care · Biotechnology: Pharmaceutical Preparations · 18 employees

HOWL vs SCYX FAQ

Which is bigger, Werewolf Therapeutics or SCYNEXIS?

Werewolf Therapeutics (HOWL) is larger, with a market capitalization of $47.60M compared with $40.69M for SCYNEXIS (SCYX).

Which stock has performed better over the past year, HOWL or SCYX?

SCYX returned -32.11% over the past 12 months, compared with -51.60% for HOWL (price return, excluding dividends). Past performance does not predict future results.

Are Werewolf Therapeutics and SCYNEXIS in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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