Heron Therapeutics (HRTX) vs Rafael (RFL)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Rafael (RFL) has outperformed Heron Therapeutics (HRTX) over the past year, gaining 9.6% versus a loss of 73.5%. Over five years, RFL leads with a -95.1% price change compared with -96.6% for HRTX. Rafael is the larger company by market cap ($82.7 million vs $75.9 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | HRTX | RFL |
|---|---|---|
| Share price | $0.3999 | $1.59 |
| Market cap | $75.92M | $82.66M |
| 1-day change | +11.64% | +7.46% |
| YTD return | -72.45% | +25.42% |
| 1-year return | -73.47% | +9.63% |
| 5-year return | -96.62% | -95.09% |
| EPS (TTM) | $-0.18 | $-0.72 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.58 | $3.96 |
| 52-week low | $0.26 | $1.12 |
| Distance from 52-week high | -74.69% | -59.86% |
| Analyst consensus | none | — |
| Avg. price target upside | +1650.44% | — |
| Average volume | 2.59M | 159.84K |
| Shares outstanding | 189.85M | 51.21M |
| Employees | 128 | 21 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- RFL has outperformed HRTX by 83.1 percentage points over the past year.
About Heron Therapeutics
HRTX stock →Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration.
Health Care · Biotechnology: Pharmaceutical Preparations · 128 employees
About Rafael
RFL stock →Rafael Holdings, Inc. primarily engages in holding interests in clinical and early-stage pharmaceutical companies, and medical devices in the United States and Israel.
Health Care · Biotechnology: Pharmaceutical Preparations · 21 employees
HRTX vs RFL FAQ
Which is bigger, Heron Therapeutics or Rafael?
Rafael (RFL) is larger, with a market capitalization of $82.66M compared with $75.92M for Heron Therapeutics (HRTX).
Which stock has performed better over the past year, HRTX or RFL?
RFL returned +9.63% over the past 12 months, compared with -73.47% for HRTX (price return, excluding dividends). Past performance does not predict future results.
Are Heron Therapeutics and Rafael in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.