MetaCap

ICU Medical (ICUI) vs Pulse Biosciences (PLSE)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Pulse Biosciences (PLSE) has outperformed ICU Medical (ICUI) over the past year, gaining 147.1% versus a gain of 32.1%. Over five years, PLSE leads with a +126.7% price change compared with -32.4% for ICUI. ICU Medical is the larger company by market cap ($3.93 billion vs $3.56 billion), about 1.1 times the size.

ICU Medical converts more of its revenue into profit, with a net margin of 0.0% versus -20794.6%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ICUI+32.12%PLSE+147.06%
+189%+71%-47%
Oct 7, 20251 yearOct 7, 2026
ICUI-31.60%PLSE+140.05%
+176%+35%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ICUI versus PLSE key metrics
MetricICUIPLSE
Share price$157.18$49.98
Market cap$3.93B$3.56B
1-day change+0.74%+1.81%
YTD return+9.36%+257.54%
1-year return+32.12%+147.06%
5-year return-32.41%+126.74%
P/E ratio (TTM)132.08—
Forward P/E16.29—
EPS (TTM)$1.19$-1.18
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$2.23B$350.00K
Revenue growth (YoY)-6.33%—
Net income (latest FY)$732.00K$-72.78M
Gross margin36.84%-54.00%
Operating margin1.92%-21982.57%
Net margin0.03%-20794.57%
52-week high$192.85$58.90
52-week low$112.50$12.56
Distance from 52-week high-18.50%-15.14%
Analyst consensusbuystrong_buy
Avg. price target upside+23.03%+13.05%
Average volume277.57K506.50K
Shares outstanding25.01M71.32M
Employees13,000116
SectorHealth CareHealth Care
IndustryMedical/Dental InstrumentsMedical/Dental Instruments

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PLSE has outperformed ICUI by 114.9 percentage points over the past year.
  • ICU Medical is more profitable, keeping 0.0 cents of every revenue dollar as net income versus -20794.6 cents for Pulse Biosciences.

About ICU Medical

ICUI stock →

ICU Medical, Inc., together with its subsidiaries, develops, manufactures, and sells medical products used in infusion therapy, vascular access, and vital care applications worldwide. It offers Clave needlefree products under the MicroClave, MicroClave Clear, and NanoClave brands; Neutron catheter patency devices; ChemoLock closed system transfer devices and ChemoClaveTM for preparation and administration of hazardous drugs; Tego needle free connectors; Deltec GRIPPER non-coring needles for portal access; ClearGuard, SwabCap, and SwabTip disinfection caps; and vascular access products.

Health Care · Medical/Dental Instruments · 13,000 employees

About Pulse Biosciences

PLSE stock →

Pulse Biosciences, Inc. operates as a novel bioelectric medicine company.

Health Care · Medical/Dental Instruments · 116 employees

ICUI vs PLSE FAQ

Which is bigger, ICU Medical or Pulse Biosciences?

ICU Medical (ICUI) is larger, with a market capitalization of $3.93B compared with $3.56B for Pulse Biosciences (PLSE).

Which stock has performed better over the past year, ICUI or PLSE?

PLSE returned +147.06% over the past 12 months, compared with +32.12% for ICUI (price return, excluding dividends). Past performance does not predict future results.

Are ICU Medical and Pulse Biosciences in the same industry?

Yes. Both are classified in the Medical/Dental Instruments industry within the Health Care sector.

More comparisons