IDEAYA Biosciences (IDYA) vs Twist Bioscience (TWST)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Twist Bioscience (TWST) has outperformed IDEAYA Biosciences (IDYA) over the past year, gaining 363.7% versus a gain of 34.4%. Over five years, IDYA leads with a +55.9% price change compared with +34.8% for TWST. Twist Bioscience is the larger company by market cap ($10.08 billion vs $3.48 billion), about 2.9 times the size, while IDEAYA Biosciences is growing revenue faster (+3024.4% vs +20.3%).
Twist Bioscience converts more of its revenue into profit, with a net margin of -20.6% versus -52.0%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | IDYA | TWST |
|---|---|---|
| Share price | $36.06 | $152.05 |
| Market cap | $3.48B | $10.08B |
| 1-day change | -0.55% | -2.31% |
| YTD return | +4.31% | +379.35% |
| 1-year return | +34.35% | +363.71% |
| 5-year return | +55.90% | +34.80% |
| EPS (TTM) | $-1.93 | $-2.23 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $218.71M | $376.57M |
| Revenue growth (YoY) | +3024.43% | +20.32% |
| Net income (latest FY) | $-113.70M | $-77.67M |
| Gross margin | — | 50.72% |
| Operating margin | -72.84% | -36.18% |
| Net margin | -51.99% | -20.63% |
| 52-week high | $42.68 | $219.71 |
| 52-week low | $26.05 | $23.30 |
| Distance from 52-week high | -15.51% | -30.80% |
| Analyst consensus | strong_buy | buy |
| Avg. price target upside | +46.28% | -1.13% |
| Average volume | 779.15K | 2.04M |
| Shares outstanding | 96.49M | 66.30M |
| Employees | 145 | 979 |
| Sector | Healthcare | Healthcare |
| Industry | Biotechnology | Biotechnology |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Twist Bioscience is about 2.9 times larger than IDEAYA Biosciences by market value ($10.08B vs $3.48B).
- TWST has outperformed IDYA by 329.4 percentage points over the past year.
- Twist Bioscience is more profitable, keeping -20.6 cents of every revenue dollar as net income versus -52.0 cents for IDEAYA Biosciences.
- IDEAYA Biosciences grew revenue faster in its latest fiscal year (+3024.43% vs +20.32%).
About IDEAYA Biosciences
IDYA stock →IDEAYA Biosciences, Inc., a precision medicine oncology company, develops targeted therapeutics for patient populations selected using molecular diagnostics in the United States. The company offers Darovasertib, an oral, potent, and selective protein kinase, C (PKC) inhibitor for the treatment of uveal melanoma, ocular cancer, and is being evaluated in multiple clinical trials as monotherapy and in combination with crizotinib for metastatic, neoadjuvant, and adjuvant settings.
Healthcare · Biotechnology · 145 employees
About Twist Bioscience
TWST stock →Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. It offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development.
Healthcare · Biotechnology · 979 employees
IDYA vs TWST FAQ
Which is bigger, IDEAYA Biosciences or Twist Bioscience?
Twist Bioscience (TWST) is larger, with a market capitalization of $10.08B compared with $3.48B for IDEAYA Biosciences (IDYA).
Which stock has performed better over the past year, IDYA or TWST?
TWST returned +363.71% over the past 12 months, compared with +34.35% for IDYA (price return, excluding dividends). Past performance does not predict future results.
Are IDEAYA Biosciences and Twist Bioscience in the same industry?
Yes. Both are classified in the Biotechnology industry within the Healthcare sector.