IDEAYA Biosciences (IDYA) vs Xenon Pharmaceuticals (XENE)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
IDEAYA Biosciences (IDYA) has outperformed Xenon Pharmaceuticals (XENE) over the past year, gaining 34.7% versus a loss of 7.9%. Over five years, IDYA leads with a +56.8% price change compared with +7.4% for XENE. Xenon Pharmaceuticals is the larger company by market cap ($3.50 billion vs $3.48 billion), about 1.0 times the size.
IDEAYA Biosciences converts more of its revenue into profit, with a net margin of -52.0% versus -4612.1%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | IDYA | XENE |
|---|---|---|
| Share price | $36.06 | $36.16 |
| Market cap | $3.48B | $3.50B |
| 1-day change | -0.55% | -0.69% |
| YTD return | +4.89% | -19.32% |
| 1-year return | +34.70% | -7.87% |
| 5-year return | +56.77% | +7.43% |
| EPS (TTM) | $-1.94 | $-4.74 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $218.71M | $7.50M |
| Revenue growth (YoY) | +3024.43% | — |
| Net income (latest FY) | $-113.70M | $-345.91M |
| Operating margin | -72.84% | -4974.27% |
| Net margin | -51.99% | -4612.13% |
| 52-week high | $42.68 | $72.66 |
| 52-week low | $26.05 | $35.06 |
| Distance from 52-week high | -15.51% | -50.23% |
| Analyst consensus | strong_buy | strong_buy |
| Avg. price target upside | +46.28% | +102.90% |
| Average volume | 785.95K | 1.43M |
| Shares outstanding | 96.49M | 96.84M |
| Employees | 145 | 358 |
| Sector | Healthcare | Health Care |
| Industry | Biotechnology | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- IDYA has outperformed XENE by 42.6 percentage points over the past year.
- IDEAYA Biosciences is more profitable, keeping -52.0 cents of every revenue dollar as net income versus -4612.1 cents for Xenon Pharmaceuticals.
- The two companies sit in different sectors: IDEAYA Biosciences in Healthcare and Xenon Pharmaceuticals in Health Care.
About IDEAYA Biosciences
IDYA stock →IDEAYA Biosciences, Inc., a precision medicine oncology company, develops targeted therapeutics for patient populations selected using molecular diagnostics in the United States. The company offers Darovasertib, an oral, potent, and selective protein kinase, C (PKC) inhibitor for the treatment of uveal melanoma, ocular cancer, and is being evaluated in multiple clinical trials as monotherapy and in combination with crizotinib for metastatic, neoadjuvant, and adjuvant settings.
Healthcare · Biotechnology · 145 employees
About Xenon Pharmaceuticals
XENE stock →Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders. Its product candidates include Azetukalner, a novel, potent Kv7 potassium channel opener which is in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major depressive disorder and bipolar depression.
Health Care · Biotechnology: Pharmaceutical Preparations · 358 employees
IDYA vs XENE FAQ
Which is bigger, IDEAYA Biosciences or Xenon Pharmaceuticals?
Xenon Pharmaceuticals (XENE) is larger, with a market capitalization of $3.50B compared with $3.48B for IDEAYA Biosciences (IDYA).
Which stock has performed better over the past year, IDYA or XENE?
IDYA returned +34.70% over the past 12 months, compared with -7.87% for XENE (price return, excluding dividends). Past performance does not predict future results.
Are IDEAYA Biosciences and Xenon Pharmaceuticals in the same industry?
No. IDEAYA Biosciences is in the Healthcare sector, while Xenon Pharmaceuticals is in Health Care.