Illumina (ILMN) vs Mettler-Toledo International (MTD)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Illumina (ILMN) has outperformed Mettler-Toledo International (MTD) over the past year, gaining 177.0% versus a gain of 17.1%. Over five years, MTD leads with a +8.2% price change compared with -32.9% for ILMN. Illumina is the larger company by market cap ($40.43 billion vs $30.73 billion), about 1.3 times the size, while Mettler-Toledo International is growing revenue faster (+4.0% vs -0.7%).
On valuation, Mettler-Toledo International trades at a lower forward P/E (29.6x vs 43.8x for Illumina). Mettler-Toledo International converts more of its revenue into profit, with a net margin of 21.6% versus 19.6%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ILMN | MTD |
|---|---|---|
| Share price | $267.76 | $1,533.48 |
| Market cap | $40.43B | $30.73B |
| 1-day change | -2.11% | +0.03% |
| YTD return | +104.15% | +9.99% |
| 1-year return | +176.95% | +17.14% |
| 5-year return | -32.85% | +8.16% |
| P/E ratio (TTM) | 49.96 | 34.55 |
| Forward P/E | 43.83 | 29.62 |
| EPS (TTM) | $5.36 | $44.38 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $4.34B | $4.03B |
| Revenue growth (YoY) | -0.66% | +3.98% |
| Net income (latest FY) | $850.00M | $869.19M |
| Gross margin | 66.08% | 59.37% |
| Operating margin | 18.58% | — |
| Net margin | 19.57% | 21.59% |
| 52-week high | $309.35 | $1,585.72 |
| 52-week low | $88.00 | $1,023.05 |
| Distance from 52-week high | -13.44% | -3.29% |
| Analyst consensus | buy | hold |
| Avg. price target upside | -16.40% | -4.04% |
| Average volume | 2.66M | 183.40K |
| Shares outstanding | 151.00M | 20.04M |
| Employees | 8,600 | 16,600 |
| Sector | Health Care | Industrials |
| Industry | Medical Specialities | Biotechnology: Laboratory Analytical Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ILMN has outperformed MTD by 159.8 percentage points over the past year.
- Illumina trades at a higher earnings multiple (50.0x vs 34.6x trailing P/E).
- The two companies sit in different sectors: Illumina in Health Care and Mettler-Toledo International in Industrials.
About Illumina
ILMN stock →Illumina, Inc. provides sequencing- and array-based solutions for genetic and genomic analysis in the Americas, Europe, Greater China, the Asia Pacific, the Middle East, and Africa.
Health Care · Medical Specialities · 8,600 employees
About Mettler-Toledo International
MTD stock →Mettler-Toledo International Inc. manufactures and supplies precision instruments and services in the Americas, Europe, Asia, and internationally.
Industrials · Biotechnology: Laboratory Analytical Instruments · 16,600 employees
ILMN vs MTD FAQ
Which is bigger, Illumina or Mettler-Toledo International?
Illumina (ILMN) is larger, with a market capitalization of $40.43B compared with $30.73B for Mettler-Toledo International (MTD).
Which stock has performed better over the past year, ILMN or MTD?
ILMN returned +176.95% over the past 12 months, compared with +17.14% for MTD (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, ILMN or MTD?
MTD has the lower trailing P/E at 34.6, versus 50.0 for ILMN. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Illumina and Mettler-Toledo International in the same industry?
No. Illumina is in the Health Care sector, while Mettler-Toledo International is in Industrials.