MetaCap

Illumina (ILMN) vs UnitedHealth Group (UNH)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Illumina (ILMN) has outperformed UnitedHealth Group (UNH) over the past year, gaining 170.6% versus a gain of 0.3%. Over five years, UNH leads with a -13.3% price change compared with -33.7% for ILMN. UnitedHealth Group is the larger company by market cap ($340.46 billion vs $42.00 billion), about 8.1 times the size.

On valuation, UnitedHealth Group trades at a lower forward P/E (16.8x vs 45.5x for Illumina). UnitedHealth Group pays a dividend yielding 2.36%, while Illumina does not currently pay one. Illumina converts more of its revenue into profit, with a net margin of 19.6% versus 2.7%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ILMN+170.58%UNH+0.28%
+212%+85%-41%
Oct 8, 20251 yearOct 8, 2026
ILMN-33.66%UNH-9.18%
+57%-16%-89%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ILMN versus UNH key metrics
MetricILMNUNH
Share price$278.17$379.30
Market cap$42.00B$340.46B
1-day change+5.14%+2.25%
YTD return+101.72%+12.37%
1-year return+170.58%+0.28%
5-year return-33.65%-13.34%
P/E ratio (TTM)51.9024.39
Forward P/E45.4616.78
EPS (TTM)$5.36$15.55
Dividend yield0.00%2.36%
Annual dividend$0.00$8.95
Revenue (latest FY)$4.34B$447.57B
Revenue growth (YoY)-0.66%+11.81%
Net income (latest FY)$850.00M$12.06B
Gross margin66.08%88.68%
Operating margin18.58%4.24%
Net margin19.57%2.69%
52-week high$309.35$461.62
52-week low$88.00$255.97
Distance from 52-week high-10.08%-17.83%
Analyst consensusbuybuy
Avg. price target upside-16.54%+27.00%
Average volume2.69M4.94M
Shares outstanding151.00M897.59M
Employees8,600390,000
SectorHealth CareHealth Care
IndustryMedical SpecialitiesMedical Specialities

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • UnitedHealth Group is about 8.1 times larger than Illumina by market value ($340.46B vs $42.00B).
  • ILMN has outperformed UNH by 170.3 percentage points over the past year.
  • Illumina trades at a higher earnings multiple (51.9x vs 24.4x trailing P/E).
  • UnitedHealth Group offers a meaningfully higher dividend yield (2.36% vs 0.00%).
  • Illumina is more profitable, keeping 19.6 cents of every revenue dollar as net income versus 2.7 cents for UnitedHealth Group.
  • UnitedHealth Group grew revenue faster in its latest fiscal year (+11.81% vs -0.66%).

About Illumina

ILMN stock →

Illumina, Inc. provides sequencing- and array-based solutions for genetic and genomic analysis in the Americas, Europe, Greater China, the Asia Pacific, the Middle East, and Africa.

Health Care · Medical Specialities · 8,600 employees

About UnitedHealth Group

UNH stock →

UnitedHealth Group Incorporated operates as a health care company in the United States and internationally. It operates through four segments: Optum Health, Optum Insight, Optum Rx; and UnitedHealthcare.

Health Care · Medical Specialities · 390,000 employees

ILMN vs UNH FAQ

Which is bigger, Illumina or UnitedHealth Group?

UnitedHealth Group (UNH) is larger, with a market capitalization of $340.46B compared with $42.00B for Illumina (ILMN).

Which stock has performed better over the past year, ILMN or UNH?

ILMN returned +170.58% over the past 12 months, compared with +0.28% for UNH (price return, excluding dividends). Past performance does not predict future results.

Which has the lower P/E ratio, ILMN or UNH?

UNH has the lower trailing P/E at 24.4, versus 51.9 for ILMN. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.

Which pays a higher dividend, Illumina or UnitedHealth Group?

UnitedHealth Group pays a dividend yielding 2.36%, while Illumina does not currently pay a regular dividend.

Are Illumina and UnitedHealth Group in the same industry?

Yes. Both are classified in the Medical Specialities industry within the Health Care sector.

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