Inspire Medical Systems (INSP) vs iRhythm (IRTC)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Inspire Medical Systems (INSP) has outperformed iRhythm (IRTC) over the past year, losing 14.0% versus a loss of 39.6%. Over five years, IRTC leads with a +41.9% price change compared with -71.9% for INSP. iRhythm is the larger company by market cap ($3.52 billion vs $1.99 billion), about 1.8 times the size.
On valuation, Inspire Medical Systems trades at a lower forward P/E (44.6x vs 83.3x for iRhythm). Inspire Medical Systems converts more of its revenue into profit, with a net margin of 15.9% versus -6.0%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | INSP | IRTC |
|---|---|---|
| Share price | $68.89 | $106.70 |
| Market cap | $1.99B | $3.52B |
| 1-day change | +3.30% | +4.00% |
| YTD return | -25.31% | -39.87% |
| 1-year return | -14.04% | -39.57% |
| 5-year return | -71.90% | +41.93% |
| P/E ratio (TTM) | 15.17 | — |
| Forward P/E | 44.59 | 83.26 |
| EPS (TTM) | $4.54 | $-0.42 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $911.98M | $747.14M |
| Revenue growth (YoY) | +13.60% | +26.24% |
| Net income (latest FY) | $145.42M | $-44.55M |
| Gross margin | 85.39% | 70.57% |
| Operating margin | 5.59% | -7.68% |
| Net margin | 15.95% | -5.96% |
| 52-week high | $147.03 | $212.00 |
| 52-week low | $38.91 | $100.70 |
| Distance from 52-week high | -53.15% | -49.67% |
| Analyst consensus | hold | strong_buy |
| Avg. price target upside | -5.65% | +63.01% |
| Average volume | 798.17K | 569.39K |
| Shares outstanding | 28.91M | 32.96M |
| Employees | 1,333 | 2,400 |
| Sector | Health Care | Health Care |
| Industry | Medical/Dental Instruments | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- INSP has outperformed IRTC by 25.5 percentage points over the past year.
- Inspire Medical Systems is more profitable, keeping 15.9 cents of every revenue dollar as net income versus -6.0 cents for iRhythm.
- iRhythm grew revenue faster in its latest fiscal year (+26.24% vs +13.60%).
About Inspire Medical Systems
INSP stock →Inspire Medical Systems, Inc., a medical technology company, focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA) in the United States and internationally. The company offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for patients with moderate to severe OSA.
Health Care · Medical/Dental Instruments · 1,333 employees
About iRhythm
IRTC stock →iRhythm Holdings, Inc., a digital healthcare company, engages in the design, development, and commercialization of device-based technology that provides ambulatory cardiac monitoring services to diagnose arrhythmias in the United States. The company offers Zio ambulatory cardiac monitoring services, including long-term and short-term continuous monitoring and mobile cardiac telemetry monitoring services.
Health Care · Medical/Dental Instruments · 2,400 employees
INSP vs IRTC FAQ
Which is bigger, Inspire Medical Systems or iRhythm?
iRhythm (IRTC) is larger, with a market capitalization of $3.52B compared with $1.99B for Inspire Medical Systems (INSP).
Which stock has performed better over the past year, INSP or IRTC?
INSP returned -14.04% over the past 12 months, compared with -39.57% for IRTC (price return, excluding dividends). Past performance does not predict future results.
Are Inspire Medical Systems and iRhythm in the same industry?
Yes. Both are classified in the Medical/Dental Instruments industry within the Health Care sector.