MetaCap

Innoviva (INVA) vs Stoke Therapeutics (STOK)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Innoviva (INVA) has outperformed Stoke Therapeutics (STOK) over the past year, gaining 22.4% versus a loss of 11.1%. Over five years, INVA leads with a +26.8% price change compared with +3.3% for STOK. Stoke Therapeutics is the larger company by market cap ($1.56 billion vs $1.51 billion), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

INVA+22.44%STOK-11.06%
+44%+11%-21%
Oct 7, 20251 yearOct 7, 2026
INVA+24.84%STOK+7.86%
+73%-10%-93%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

INVA versus STOK key metrics
MetricINVASTOK
Share price$20.88$24.17
Market cap$1.51B$1.56B
1-day change-0.85%-0.51%
YTD return+5.35%-23.47%
1-year return+22.44%-11.06%
5-year return+26.79%+3.27%
P/E ratio (TTM)4.88—
Forward P/E9.45—
EPS (TTM)$4.28$-3.38
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$25.15$40.22
52-week low$16.52$20.32
Distance from 52-week high-16.98%-39.92%
Analyst consensusbuystrong_buy
Avg. price target upside+67.62%+92.26%
Average volume819.96K852.03K
Shares outstanding72.25M64.53M
Employees159170
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • INVA has outperformed STOK by 33.5 percentage points over the past year.

About Innoviva

INVA stock →

Innoviva, Inc. operates as a biopharmaceutical company in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 159 employees

About Stoke Therapeutics

STOK stock →

Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression.

Health Care · Biotechnology: Pharmaceutical Preparations · 170 employees

INVA vs STOK FAQ

Which is bigger, Innoviva or Stoke Therapeutics?

Stoke Therapeutics (STOK) is larger, with a market capitalization of $1.56B compared with $1.51B for Innoviva (INVA).

Which stock has performed better over the past year, INVA or STOK?

INVA returned +22.44% over the past 12 months, compared with -11.06% for STOK (price return, excluding dividends). Past performance does not predict future results.

Are Innoviva and Stoke Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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