MetaCap

Invivyd (IVVD) vs Palisade Bio (PALI)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Palisade Bio (PALI) has outperformed Invivyd (IVVD) over the past year, losing 27.5% versus a loss of 55.3%. Over five years, IVVD leads with a -97.8% price change compared with -99.9% for PALI. Palisade Bio is the larger company by market cap ($252.7 million vs $206.4 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

IVVD-55.57%PALI-26.00%
+83%+4%-75%
Oct 8, 20251 yearOct 7, 2026
IVVD-97.88%PALI-99.92%
+40%-33%-107%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

IVVD versus PALI key metrics
MetricIVVDPALI
Share price$0.7004$1.45
Market cap$206.45M$252.69M
1-day change-3.87%-2.03%
YTD return-70.50%-38.30%
1-year return-55.30%-27.50%
5-year return-97.75%-99.93%
P/E ratio (TTM)—2.42
EPS (TTM)$-0.33$0.60
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.07$2.86
52-week low$0.528$1.32
Distance from 52-week high-77.19%-49.30%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+1327.76%+604.83%
Average volume4.78M2.56M
Shares outstanding294.76M174.27M
Employees12214
SectorHealthcareHealth Care
IndustryBiotechnologyBiotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PALI has outperformed IVVD by 27.8 percentage points over the past year.
  • The two companies sit in different sectors: Invivyd in Healthcare and Palisade Bio in Health Care.

About Invivyd

IVVD stock →

Invivyd, Inc., together with its subsidiaries, engages in the research, development, commercialization, and sale of antibody therapies for the prevention and treatment of viral infectious diseases in the United States. The company offers Pemivibart, a half-life extended investigational monoclonal antibody for the pre-exposure prophylaxis prevention of COVID-19 in adults and adolescents through injection under the PEMGARDA brand.

Healthcare · Biotechnology · 122 employees

About Palisade Bio

PALI stock →

Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn's disease.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 14 employees

IVVD vs PALI FAQ

Which is bigger, Invivyd or Palisade Bio?

Palisade Bio (PALI) is larger, with a market capitalization of $252.69M compared with $206.45M for Invivyd (IVVD).

Which stock has performed better over the past year, IVVD or PALI?

PALI returned -27.50% over the past 12 months, compared with -55.30% for IVVD (price return, excluding dividends). Past performance does not predict future results.

Are Invivyd and Palisade Bio in the same industry?

No. Invivyd is in the Healthcare sector, while Palisade Bio is in Health Care.

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