MetaCap

Keros Therapeutics (KROS) vs Pyxis Oncology (PYXS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Keros Therapeutics (KROS) has outperformed Pyxis Oncology (PYXS) over the past year, losing 27.1% versus a loss of 31.6%. Over five years, KROS leads with a -70.1% price change compared with -83.1% for PYXS. Pyxis Oncology is the larger company by market cap ($238.9 million vs $232.9 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

KROS-27.07%PYXS-31.62%
+91%+10%-71%
Oct 8, 20251 yearOct 8, 2026
KROS-68.50%PYXS-84.92%
+100%-1%-102%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

KROS versus PYXS key metrics
MetricKROSPYXS
Share price$11.74$2.00
Market cap$232.86M$238.91M
1-day change+0.90%+0.50%
YTD return-42.83%+73.04%
1-year return-27.07%-31.62%
5-year return-70.15%-83.09%
EPS (TTM)$-3.22$-1.40
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$22.55$5.55
52-week low$9.69$1.03
Distance from 52-week high-47.92%-63.96%
Analyst consensusbuynone
Avg. price target upside+68.84%+333.50%
Average volume194.05K1.26M
Shares outstanding19.83M119.46M
Employees9256
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Keros Therapeutics

KROS stock →

Keros Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops and commercializes novel therapeutics to treat patients with disorders linked to dysfunctional signaling of the transforming growth factor-beta family of proteins in the United States. It develops rinvatercept, which acts as a ligand trap and inhibits the biological effects of myostatin and activin A in Phase 1 clinical trials for Duchenne Muscular Dystrophy and Amyotrophic Lateral Sclerosis; and elritercept to target TGF-ß signaling pathways to address diseases that arise from ineffective hematopoiesis in Phase 3 clinical trials for Myelodysplastic Syndromes and Phase 2 clinical trials for Myelofibrosis.

Health Care · Biotechnology: Pharmaceutical Preparations · 92 employees

About Pyxis Oncology

PYXS stock →

Pyxis Oncology, Inc., a clinical stage company, engages in the development of therapeutics to treat solid tumors. Its lead antibody-drug conjugates (ADC) product candidate is PYX-201, an investigational novel ADC consisting of human immunoglobulin G1 (IgG1), which is in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; PYX-102, an investigational immunotherapeutic targeting KLRG1, an inhibitory receptor on T cells and NK cells, with potential for use as monotherapy or in combination treatments; and lead immuno-oncology (IO) product candidate is PYX-106, an investigational fully human IgG1 Siglec-15-targeting antibody that is in Phase 1 clinical trial to treat patients with advanced solid tumors.

Health Care · Biotechnology: Pharmaceutical Preparations · 56 employees

KROS vs PYXS FAQ

Which is bigger, Keros Therapeutics or Pyxis Oncology?

Pyxis Oncology (PYXS) is larger, with a market capitalization of $238.91M compared with $232.86M for Keros Therapeutics (KROS).

Which stock has performed better over the past year, KROS or PYXS?

KROS returned -27.07% over the past 12 months, compared with -31.62% for PYXS (price return, excluding dividends). Past performance does not predict future results.

Are Keros Therapeutics and Pyxis Oncology in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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