MetaCap

Lakefront Biotherapeutics (LKFT) vs UroGen Pharma (URGN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

UroGen Pharma (URGN) has outperformed Lakefront Biotherapeutics (LKFT) over the past year, gaining 113.4% versus a loss of 14.5%. Over five years, URGN leads with a +117.3% price change compared with -44.9% for LKFT. Lakefront Biotherapeutics is the larger company by market cap ($1.93 billion vs $1.81 billion), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

LKFT-14.46%URGN+113.39%
+201%+83%-35%
Oct 8, 20251 yearOct 8, 2026
LKFT-40.75%URGN+132.87%
+218%+65%-87%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

LKFT versus URGN key metrics
MetricLKFTURGN
Share price$29.51$36.98
Market cap$1.93B$1.81B
1-day change-1.63%-9.14%
YTD return-9.76%+57.90%
1-year return-14.46%+113.39%
5-year return-44.86%+117.27%
P/E ratio (TTM)2.81—
Forward P/E—13.23
EPS (TTM)$10.52$-1.97
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$109.79M
Revenue growth (YoY)—+21.45%
Net income (latest FY)—$-153.49M
Gross margin—88.66%
Operating margin—-113.73%
Net margin—-139.81%
52-week high$36.24$50.81
52-week low$25.68$15.86
Distance from 52-week high-18.57%-27.22%
Analyst consensusholdstrong_buy
Avg. price target upside+2.27%+62.25%
Average volume273.30K849.01K
Shares outstanding65.48M48.88M
Employees196300
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • URGN has outperformed LKFT by 127.9 percentage points over the past year.

About Lakefront Biotherapeutics

LKFT stock →

Lakefront Biotherapeutics NV, a biotechnology company, develops medicines focusing on oncology and immunology primarily in the United States and Europe. The company's pipeline products comprise GLPG3667, which is in a phase 2 clinical trial in dermatomyositis and systemic lupus erythematosus; GLPG5101, a CD19 CAR-T product candidate manufactured at point-of-care, currently in a phase 1/2 trial in relapsed/refractory non-hodgkin lymphoma; and GLPG5301, a BCMA CAR-T product candidate manufactured at point-of-care, currently in phase 1/2 in relapsed/refractory multiple myeloma.

Health Care · Biotechnology: Pharmaceutical Preparations · 196 employees

About UroGen Pharma

URGN stock →

UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty cancers. It offers RTGel, a novel proprietary polymeric biocompatible, reverse thermal gelation hydrogel technology; Mitomycin a generic drug used off-label as an adjuvant chemotherapy for the treatment of low-grade NMIBC after trans-urethral resection of bladder tumor; Zusduri, a sustained-release formulation of mitomycin for the treatment of non-muscle invasive bladder cancer (NMIBC); and Jelmyto for pyelocalyceal solutions.

Health Care · Biotechnology: Pharmaceutical Preparations · 300 employees

LKFT vs URGN FAQ

Which is bigger, Lakefront Biotherapeutics or UroGen Pharma?

Lakefront Biotherapeutics (LKFT) is larger, with a market capitalization of $1.93B compared with $1.81B for UroGen Pharma (URGN).

Which stock has performed better over the past year, LKFT or URGN?

URGN returned +113.39% over the past 12 months, compared with -14.46% for LKFT (price return, excluding dividends). Past performance does not predict future results.

Are Lakefront Biotherapeutics and UroGen Pharma in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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