MetaCap

Lantheus (LNTH) vs Oruka Therapeutics (ORKA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Oruka Therapeutics (ORKA) has outperformed Lantheus (LNTH) over the past year, gaining 286.5% versus a gain of 93.2%. Over five years, LNTH leads with a +330.7% price change compared with +137.5% for ORKA. Lantheus is the larger company by market cap ($6.54 billion vs $5.26 billion), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

LNTH+93.25%ORKA+286.49%
+472%+224%-25%
Oct 7, 20251 yearOct 7, 2026
LNTH+322.17%ORKA+144.46%
+445%+172%-101%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

LNTH versus ORKA key metrics
MetricLNTHORKA
Share price$100.18$79.50
Market cap$6.54B$5.26B
1-day change+0.23%-0.85%
YTD return+50.53%+162.29%
1-year return+93.25%+286.49%
5-year return+330.70%+137.46%
P/E ratio (TTM)24.26—
Forward P/E15.71—
EPS (TTM)$4.13$-2.04
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$1.54B—
Revenue growth (YoY)+0.50%—
Net income (latest FY)$233.56M$-105.43M
Gross margin61.10%—
Operating margin20.16%—
Net margin15.15%—
52-week high$111.86$115.52
52-week low$50.16$21.66
Distance from 52-week high-10.44%-31.18%
Analyst consensusnonestrong_buy
Avg. price target upside+7.55%+94.97%
Average volume1.32M886.21K
Shares outstanding65.30M66.21M
Employees1,19368
SectorHealth CareHealth Care
IndustryBiotechnology: In Vitro & In Vivo Diagnostic SubstancesBiotechnology: In Vitro & In Vivo Diagnostic Substances

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ORKA has outperformed LNTH by 193.2 percentage points over the past year.

About Lantheus

LNTH stock →

Lantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in diagnosis and treatment of heart, cancer, and other diseases worldwide.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 1,193 employees

About Oruka Therapeutics

ORKA stock →

Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 68 employees

LNTH vs ORKA FAQ

Which is bigger, Lantheus or Oruka Therapeutics?

Lantheus (LNTH) is larger, with a market capitalization of $6.54B compared with $5.26B for Oruka Therapeutics (ORKA).

Which stock has performed better over the past year, LNTH or ORKA?

ORKA returned +286.49% over the past 12 months, compared with +93.25% for LNTH (price return, excluding dividends). Past performance does not predict future results.

Are Lantheus and Oruka Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: In Vitro & In Vivo Diagnostic Substances industry within the Health Care sector.

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