MetaCap

Lyell Immunopharma (LYEL) vs Whitehawk Therapeutics (WHWK)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Whitehawk Therapeutics (WHWK) has outperformed Lyell Immunopharma (LYEL) over the past year, gaining 62.9% versus a loss of 51.9%. Over five years, WHWK leads with a -87.2% price change compared with -96.7% for LYEL. Lyell Immunopharma is the larger company by market cap ($213.4 million vs $200.7 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

LYEL-51.86%WHWK+62.91%
+149%+43%-63%
Oct 8, 20251 yearOct 8, 2026
LYEL-96.60%WHWK-86.64%
+13%-45%-102%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

LYEL versus WHWK key metrics
MetricLYELWHWK
Share price$8.71$3.52
Market cap$213.44M$200.67M
1-day change-0.91%+1.44%
YTD return-71.44%+43.39%
1-year return-51.86%+62.91%
5-year return-96.69%-87.25%
EPS (TTM)$-12.86$-1.14
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$45.00$5.50
52-week low$8.21$1.87
Distance from 52-week high-80.64%-35.94%
Analyst consensusbuybuy
Avg. price target upside+334.90%+119.03%
Average volume145.70K367.72K
Shares outstanding24.51M57.01M
Employees16132
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • WHWK has outperformed LYEL by 114.8 percentage points over the past year.

About Lyell Immunopharma

LYEL stock →

Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The company's lead product candidate include rondecabtagene autoleucel, an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development, which is in pivotal PiNACLE trial in the 3L+ setting and in a Phase 1/2 clinical trial in the 2L setting, as well as a second pivotal trial, PiNACLE-H2H, which is a Phase 3 head-to-head CAR T cell therapy randomized controlled trial of ronde-cel for LBCL in the 2L setting for the treatment of large B-cell lymphoma; and LYL273, a GCC-targeted CAR T-cell product candidate enhanced with CD19 CAR expression and controlled cytokine release designed to improve CAR T-cell expansion, immune cell infiltration, and cancer cell killing in the hostile solid tumor microenvironment, which is in Phase 1 clinical trial for the treatment of refractory metastatic colorectal cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 161 employees

About Whitehawk Therapeutics

WHWK stock →

Whitehawk Therapeutics, Inc., a clinical-stage oncology therapeutics company that develops technologies to establish tumor biology for cancer treatments. It provides three next generation antibody drug conjugates (ADC) portfolio to treat cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 32 employees

LYEL vs WHWK FAQ

Which is bigger, Lyell Immunopharma or Whitehawk Therapeutics?

Lyell Immunopharma (LYEL) is larger, with a market capitalization of $213.44M compared with $200.67M for Whitehawk Therapeutics (WHWK).

Which stock has performed better over the past year, LYEL or WHWK?

WHWK returned +62.91% over the past 12 months, compared with -51.86% for LYEL (price return, excluding dividends). Past performance does not predict future results.

Are Lyell Immunopharma and Whitehawk Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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