MetaCap

MacroGenics (MGNX) vs Sol-Gel Technologies (SLGL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

MacroGenics (MGNX) has outperformed Sol-Gel Technologies (SLGL) over the past year, gaining 106.4% versus a gain of 75.5%. Over five years, SLGL leads with a -22.8% price change compared with -82.0% for MGNX. Sol-Gel Technologies is the larger company by market cap ($230.3 million vs $226.1 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

MGNX+106.40%SLGL+75.52%
+193%+79%-36%
Oct 7, 20251 yearOct 7, 2026
MGNX-82.79%SLGL-25.06%
+11%-45%-101%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

MGNX versus SLGL key metrics
MetricMGNXSLGL
Share price$3.55$70.34
Market cap$226.14M$230.29M
1-day change0.00%-2.23%
YTD return+120.50%+70.73%
1-year return+106.40%+75.52%
5-year return-82.02%-22.85%
EPS (TTM)$-1.70$-5.61
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$5.08$97.97
52-week low$1.29$28.81
Distance from 52-week high-30.12%-28.20%
Analyst consensusbuystrong_buy
Avg. price target upside+125.35%+116.80%
Average volume621.73K55.30K
Shares outstanding63.70M3.27M
Employees29328
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • MGNX has outperformed SLGL by 30.9 percentage points over the past year.

About MacroGenics

MGNX stock →

MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States. The company's product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resistant ovarian cancer and clear cell gynecologic cancer which has completed phase 1 clinical trial; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload; MGC028, an antibody-drug conjugates (ADC) that targets ADAM9 and delivers a novel TOP1i-based linker-payload for the treatment of solid tumors, which is in phase 1 clinical trials; MGC030, a ADC molecule that targets an undisclosed antigen expressed across several solid tumors, which is in preclinical trials.

Health Care · Biotechnology: Pharmaceutical Preparations · 293 employees

About Sol-Gel Technologies

SLGL stock →

Sol-Gel Technologies Ltd., together with its subsidiary Sol-Gel Technologies Inc., develops topical dermatological drugs for patients with severe skin conditions in Israel, China, Switzerland, Canada, the United States and internationally. The company offers Twyneo, a once-daily, non-antibiotic topical cream for the treatment of acne vulgaris; and Epsolay, a once-daily topical cream for the treatment of papulopustular (subtype II) rosacea.

Health Care · Biotechnology: Pharmaceutical Preparations · 28 employees

MGNX vs SLGL FAQ

Which is bigger, MacroGenics or Sol-Gel Technologies?

Sol-Gel Technologies (SLGL) is larger, with a market capitalization of $230.29M compared with $226.14M for MacroGenics (MGNX).

Which stock has performed better over the past year, MGNX or SLGL?

MGNX returned +106.40% over the past 12 months, compared with +75.52% for SLGL (price return, excluding dividends). Past performance does not predict future results.

Are MacroGenics and Sol-Gel Technologies in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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