MetaCap

Mirum Pharmaceuticals (MIRM) vs PTC Therapeutics (PTCT)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Mirum Pharmaceuticals (MIRM) has outperformed PTC Therapeutics (PTCT) over the past year, gaining 9.4% versus a loss of 1.1%. Over five years, MIRM leads with a +371.0% price change compared with +66.0% for PTCT. Mirum Pharmaceuticals is the larger company by market cap ($5.28 billion vs $5.22 billion), about 1.0 times the size, while PTC Therapeutics is growing revenue faster (+114.5% vs +54.7%).

PTC Therapeutics converts more of its revenue into profit, with a net margin of 39.4% versus -4.5%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

MIRM+9.36%PTCT-1.06%
+79%+31%-17%
Oct 7, 20251 yearOct 7, 2026
MIRM+383.45%PTCT+72.15%
+688%+302%-85%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

MIRM versus PTCT key metrics
MetricMIRMPTCT
Share price$81.35$62.56
Market cap$5.28B$5.22B
1-day change+0.88%-1.06%
YTD return+2.09%-16.76%
1-year return+9.36%-1.06%
5-year return+371.03%+66.00%
Forward P/E—23.37
EPS (TTM)$-14.10$-0.65
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$521.31M$1.73B
Revenue growth (YoY)+54.74%+114.51%
Net income (latest FY)$-23.36M$682.64M
Operating margin-4.25%50.09%
Net margin-4.48%39.44%
52-week high$130.00$90.87
52-week low$63.23$61.23
Distance from 52-week high-37.42%-31.15%
Analyst consensusstrong_buybuy
Avg. price target upside+79.21%+62.71%
Average volume698.74K1.14M
Shares outstanding64.93M83.46M
Employees433991
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • MIRM has outperformed PTCT by 10.4 percentage points over the past year.
  • PTC Therapeutics is more profitable, keeping 39.4 cents of every revenue dollar as net income versus -4.5 cents for Mirum Pharmaceuticals.
  • PTC Therapeutics grew revenue faster in its latest fiscal year (+114.51% vs +54.74%).

About Mirum Pharmaceuticals

MIRM stock →

Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 433 employees

About PTC Therapeutics

PTCT stock →

PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to children and adults living with rare disorders in the United States and internationally. The company provides Translarna and Emflaza for the treatment of Duchenne muscular dystrophy; Upstaza to treat aromatic l-amino acid decarboxylas (AADC) deficiency, a central nervous system disorder; Tegsedi and Waylivra for the treatment of rare diseases; and Evrysdi to treat spinal muscular atrophy (SMA) in adults and children.

Health Care · Biotechnology: Pharmaceutical Preparations · 991 employees

MIRM vs PTCT FAQ

Which is bigger, Mirum Pharmaceuticals or PTC Therapeutics?

Mirum Pharmaceuticals (MIRM) is larger, with a market capitalization of $5.28B compared with $5.22B for PTC Therapeutics (PTCT).

Which stock has performed better over the past year, MIRM or PTCT?

MIRM returned +9.36% over the past 12 months, compared with -1.06% for PTCT (price return, excluding dividends). Past performance does not predict future results.

Are Mirum Pharmaceuticals and PTC Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

More comparisons