MetaCap

MoonLake Immunotherapeutics (MLTX) vs Rigel Pharmaceuticals (RIGL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Rigel Pharmaceuticals (RIGL) has outperformed MoonLake Immunotherapeutics (MLTX) over the past year, gaining 62.7% versus a gain of 16.1%. Over five years, RIGL leads with a +42.0% price change compared with +8.6% for MLTX. MoonLake Immunotherapeutics is the larger company by market cap ($916.6 million vs $896.4 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

MLTX+16.06%RIGL+62.68%
+146%+63%-21%
Oct 7, 20251 yearOct 7, 2026
MLTX+7.70%RIGL+39.51%
+563%+226%-111%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

MLTX versus RIGL key metrics
MetricMLTXRIGL
Share price$10.77$47.99
Market cap$916.60M$896.45M
1-day change-1.64%+4.08%
YTD return-18.29%+12.05%
1-year return+16.06%+62.68%
5-year return+8.57%+41.98%
P/E ratio (TTM)—2.84
Forward P/E—9.72
EPS (TTM)$-3.83$16.88
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$23.29$52.24
52-week low$8.80$24.95
Distance from 52-week high-53.76%-8.14%
Analyst consensusbuynone
Avg. price target upside+165.00%+31.28%
Average volume1.44M291.58K
Shares outstanding85.11M18.68M
Employees130172
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • RIGL has outperformed MLTX by 46.6 percentage points over the past year.

About MoonLake Immunotherapeutics

MLTX stock →

MoonLake Immunotherapeutics, a clinical-stage biotechnology company, focuses on developing therapies for inflammatory skin and joint diseases. It develops Sonelokimab, a novel tri-specific IL-17A and IL-17F inhibiting Nanobody for the treatment of inflammatory diseases in dermatology and rheumatology, as well as for hidradenitis suppurativa, psoriatic arthritis, axial spondyloarthritis, palmoplantar pustulosis, and psoriasis.

Health Care · Biotechnology: Pharmaceutical Preparations · 130 employees

About Rigel Pharmaceuticals

RIGL stock →

Rigel Pharmaceuticals, Inc., a biotechnology company, develops and provides therapies that enhance the lives of patients with hematologic disorders and cancer in the United States. The company offers TAVALISSE, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia; REZLIDHIA, a non-intensive monotherapy to treat adult patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation as detected by an FDA-approved test; and GAVRETO, a once daily, small molecule, oral, kinase inhibitor for the treatment of adult patients with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), as well as to treat adult and pediatric patients twelve years of age and older with advanced or metastatic RET fusion-positive thyroid cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 172 employees

MLTX vs RIGL FAQ

Which is bigger, MoonLake Immunotherapeutics or Rigel Pharmaceuticals?

MoonLake Immunotherapeutics (MLTX) is larger, with a market capitalization of $916.60M compared with $896.45M for Rigel Pharmaceuticals (RIGL).

Which stock has performed better over the past year, MLTX or RIGL?

RIGL returned +62.68% over the past 12 months, compared with +16.06% for MLTX (price return, excluding dividends). Past performance does not predict future results.

Are MoonLake Immunotherapeutics and Rigel Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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