MannKind (MNKD) vs OPKO Health (OPK)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
OPKO Health (OPK) has outperformed MannKind (MNKD) over the past year, losing 9.7% versus a loss of 38.9%. Over five years, MNKD leads with a -32.2% price change compared with -62.6% for OPK. MannKind is the larger company by market cap ($1.10 billion vs $1.02 billion), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | MNKD | OPK |
|---|---|---|
| Share price | $3.43 | $1.36 |
| Market cap | $1.10B | $1.02B |
| 1-day change | -0.58% | -2.15% |
| YTD return | -39.15% | +10.32% |
| 1-year return | -38.94% | -9.74% |
| 5-year return | -32.22% | -62.63% |
| Forward P/E | 26.90 | — |
| EPS (TTM) | $-0.14 | $-0.09 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $6.51 | $1.75 |
| 52-week low | $2.23 | $0.98 |
| Distance from 52-week high | -47.31% | -22.29% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +128.57% | +222.06% |
| Average volume | 4.48M | 3.35M |
| Shares outstanding | 321.54M | 746.33M |
| Employees | 591 | 2,275 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- OPK has outperformed MNKD by 29.2 percentage points over the past year.
About MannKind
MNKD stock →MannKind Corporation, a biopharmaceutical company, focuses on the provision of various solutions for transforming chronic disease care. It develops and commercializes treatments that address various unmet medical needs, including diabetes, pulmonary hypertension, and fluid overload in heart failure and chronic kidney disease.
Health Care · Biotechnology: Pharmaceutical Preparations · 591 employees
About OPKO Health
OPK stock →OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally.
Health Care · Biotechnology: Pharmaceutical Preparations · 2,275 employees
MNKD vs OPK FAQ
Which is bigger, MannKind or OPKO Health?
MannKind (MNKD) is larger, with a market capitalization of $1.10B compared with $1.02B for OPKO Health (OPK).
Which stock has performed better over the past year, MNKD or OPK?
OPK returned -9.74% over the past 12 months, compared with -38.94% for MNKD (price return, excluding dividends). Past performance does not predict future results.
Are MannKind and OPKO Health in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.