MetaCap

Monopar Therapeutics (MNPR) vs Neurogene (NGNE)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Neurogene (NGNE) has outperformed Monopar Therapeutics (MNPR) over the past year, gaining 2.6% versus a loss of 14.8%. Over five years, MNPR leads with a +242.1% price change compared with -81.6% for NGNE. Monopar Therapeutics is the larger company by market cap ($549.6 million vs $545.5 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

MNPR-14.80%NGNE+2.59%
+72%+8%-55%
Oct 8, 20251 yearOct 8, 2026
MNPR+265.93%NGNE-80.05%
+445%+163%-119%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

MNPR versus NGNE key metrics
MetricMNPRNGNE
Share price$81.89$27.26
Market cap$549.63M$545.51M
1-day change-2.49%+2.87%
YTD return+28.61%+28.64%
1-year return-14.80%+2.59%
5-year return+242.08%-81.65%
EPS (TTM)$-2.20$-5.04
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$124.82$43.66
52-week low$50.07$15.93
Distance from 52-week high-34.40%-37.56%
Analyst consensusstrong_buynone
Avg. price target upside+58.66%+185.69%
Average volume213.15K247.13K
Shares outstanding6.71M20.01M
Employees22131
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • NGNE has outperformed MNPR by 17.4 percentage points over the past year.

About Monopar Therapeutics

MNPR stock →

Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and MNPR-101-Zr, which is in phase 1 imaging and dosimetry clinical trial, a radiopharmaceutical imaging agent comprised of MNPR-101 conjugated to zirconium-89.

Health Care · Biotechnology: Pharmaceutical Preparations · 22 employees

About Neurogene

NGNE stock →

Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 131 employees

MNPR vs NGNE FAQ

Which is bigger, Monopar Therapeutics or Neurogene?

Monopar Therapeutics (MNPR) is larger, with a market capitalization of $549.63M compared with $545.51M for Neurogene (NGNE).

Which stock has performed better over the past year, MNPR or NGNE?

NGNE returned +2.59% over the past 12 months, compared with -14.80% for MNPR (price return, excluding dividends). Past performance does not predict future results.

Are Monopar Therapeutics and Neurogene in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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