MetaCap

Organogenesis (ORGO) vs PepGen (PEPG)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

PepGen (PEPG) has outperformed Organogenesis (ORGO) over the past year, losing 51.1% versus a loss of 68.1%. Organogenesis is the larger company by market cap ($169.9 million vs $166.0 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ORGO-68.12%PEPG-51.12%
+64%-7%-79%
Oct 7, 20251 yearOct 7, 2026
ORGO-78.74%PEPG-81.38%
+51%-24%-98%
May 2, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ORGO versus PEPG key metrics
MetricORGOPEPG
Share price$1.32$2.40
Market cap$169.85M$166.01M
1-day change-1.49%+3.90%
YTD return-74.52%-63.13%
1-year return-68.12%-51.12%
5-year return-87.95%—
EPS (TTM)$-0.82$-1.01
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.08$7.80
52-week low$1.28$1.31
Distance from 52-week high-81.35%-69.23%
Analyst consensusnonenone
Avg. price target upside+51.52%+324.58%
Average volume772.97K976.87K
Shares outstanding128.67M69.17M
Employees85457
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PEPG has outperformed ORGO by 17.0 percentage points over the past year.

About Organogenesis

ORGO stock →

Organogenesis Holdings Inc., a regenerative medicine company, develops, manufactures, and commercializes products for the advanced wound care, and surgical and sports medicine markets in the United States. Its advanced wound care products include Affinity and Novachor, which are amnion and chorion placental allografts for use in the care of chronic and acute wounds as protective barriers and extracellular matrix (ECM) scaffolds; Apligraf, a bioengineered bi-layered skin substitute for the treatment of venous leg ulcers and diabetic foot ulcers (DFU); Dermagraft, a dermal substitute grown from human dermal fibroblasts to treat DFUs; NuShield, a dehydrated placental allograft and surgical barrier to provide a protective barrier and ECM scaffold to support native healing; PuraPly Antimicrobial (AM) and PuraPly SX, which are antimicrobial barriers for the management of open wounds in surgical settings; and CYGNUS Dual, VIA Matrix, and SimpliMax are placental tissue grafts used to treat chronic and acute wounds that can be stored at room temperature.

Health Care · Biotechnology: Pharmaceutical Preparations · 854 employees

About PepGen

PEPG stock →

PepGen Inc., a clinical-stage biotechnology company, develops oligonucleotide therapeutics for the treatment of severe neuromuscular and neurologic diseases in the United States. The company engages in the development of PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 2 clinical trial for the treatment of myotonic dystrophy type 1; and FREEDOM2-DM1, which is in Phase 2 for the treatment of myotonic dystrophy type 1.

Health Care · Biotechnology: Pharmaceutical Preparations · 57 employees

ORGO vs PEPG FAQ

Which is bigger, Organogenesis or PepGen?

Organogenesis (ORGO) is larger, with a market capitalization of $169.85M compared with $166.01M for PepGen (PEPG).

Which stock has performed better over the past year, ORGO or PEPG?

PEPG returned -51.12% over the past 12 months, compared with -68.12% for ORGO (price return, excluding dividends). Past performance does not predict future results.

Are Organogenesis and PepGen in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

More comparisons