Pacific Biosciences of California (PACB) vs Profound Medical (PROF)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.
Summary
Pacific Biosciences of California (PACB) has outperformed Profound Medical (PROF) over the past year, gaining 52.3% versus a gain of 4.1%. Over five years, PROF leads with a -54.0% price change compared with -90.4% for PACB. Pacific Biosciences of California is the larger company by market cap ($724.2 million vs $252.1 million), about 2.9 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PACB | PROF |
|---|---|---|
| Share price | $2.33 | $6.90 |
| Market cap | $724.24M | $252.13M |
| 1-day change | +1.30% | -0.14% |
| YTD return | +24.60% | -12.33% |
| 1-year return | +52.29% | +4.07% |
| 5-year return | -90.45% | -54.03% |
| EPS (TTM) | $-0.43 | $-0.99 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.44 | $8.95 |
| 52-week low | $1.07 | $4.80 |
| Distance from 52-week high | -32.27% | -22.91% |
| Analyst consensus | buy | strong_buy |
| Avg. price target upside | +3.00% | +61.45% |
| Average volume | 10.48M | 174.11K |
| Shares outstanding | 310.83M | 36.54M |
| Employees | 485 | 162 |
| Sector | Industrials | Health Care |
| Industry | Biotechnology: Laboratory Analytical Instruments | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Pacific Biosciences of California is about 2.9 times larger than Profound Medical by market value ($724.24M vs $252.13M).
- PACB has outperformed PROF by 48.2 percentage points over the past year.
- The two companies sit in different sectors: Pacific Biosciences of California in Industrials and Profound Medical in Health Care.
About Pacific Biosciences of California
PACB stock →Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems.
Industrials · Biotechnology: Laboratory Analytical Instruments · 485 employees
About Profound Medical
PROF stock →Profound Medical Corp. operates as a commercial-stage medical device company that develops and markets AI-powered, MRI-guided, incision-free therapeutic systems for the image guided ablation of diseased tissue.
Health Care · Medical/Dental Instruments · 162 employees
PACB vs PROF FAQ
Which is bigger, Pacific Biosciences of California or Profound Medical?
Pacific Biosciences of California (PACB) is larger, with a market capitalization of $724.24M compared with $252.13M for Profound Medical (PROF).
Which stock has performed better over the past year, PACB or PROF?
PACB returned +52.29% over the past 12 months, compared with +4.07% for PROF (price return, excluding dividends). Past performance does not predict future results.
Are Pacific Biosciences of California and Profound Medical in the same industry?
No. Pacific Biosciences of California is in the Industrials sector, while Profound Medical is in Health Care.