MetaCap

Pacific Biosciences of California (PACB) vs QuidelOrtho (QDEL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Pacific Biosciences of California (PACB) has outperformed QuidelOrtho (QDEL) over the past year, gaining 52.3% versus a loss of 55.6%. Over five years, PACB leads with a -88.8% price change compared with -90.4% for QDEL. QuidelOrtho is the larger company by market cap ($851.0 million vs $714.9 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PACB+94.29%QDEL-55.58%
+113%+20%-73%
Oct 7, 20251 yearOct 7, 2026
PACB-89.07%QDEL-91.08%
+23%-40%-102%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PACB versus QDEL key metrics
MetricPACBQDEL
Share price$2.30$12.41
Market cap$714.91M$851.02M
1-day change-15.44%+0.81%
YTD return+22.99%-56.90%
1-year return+52.32%-55.58%
5-year return-88.85%-90.40%
Forward P/E—8.61
EPS (TTM)$-0.43$-15.39
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.44$35.58
52-week low$1.07$9.92
Distance from 52-week high-33.14%-65.12%
Analyst consensusbuyhold
Avg. price target upside-6.09%+18.21%
Average volume10.10M1.49M
Shares outstanding310.83M68.58M
Employees4856,500
SectorIndustrialsHealth Care
IndustryBiotechnology: Laboratory Analytical InstrumentsBiotechnology: In Vitro & In Vivo Diagnostic Substances

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PACB has outperformed QDEL by 107.9 percentage points over the past year.
  • The two companies sit in different sectors: Pacific Biosciences of California in Industrials and QuidelOrtho in Health Care.

About Pacific Biosciences of California

PACB stock →

Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems.

Industrials · Biotechnology: Laboratory Analytical Instruments · 485 employees

About QuidelOrtho

QDEL stock →

QuidelOrtho Corporation provides diagnostic testing solutions. The company operates through Labs, Transfusion Medicine, Point of Care, and Molecular Diagnostics business units.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 6,500 employees

PACB vs QDEL FAQ

Which is bigger, Pacific Biosciences of California or QuidelOrtho?

QuidelOrtho (QDEL) is larger, with a market capitalization of $851.02M compared with $714.91M for Pacific Biosciences of California (PACB).

Which stock has performed better over the past year, PACB or QDEL?

PACB returned +52.32% over the past 12 months, compared with -55.58% for QDEL (price return, excluding dividends). Past performance does not predict future results.

Are Pacific Biosciences of California and QuidelOrtho in the same industry?

No. Pacific Biosciences of California is in the Industrials sector, while QuidelOrtho is in Health Care.

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