Pacific Biosciences of California (PACB) vs SI-BONE (SIBN)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Pacific Biosciences of California (PACB) has outperformed SI-BONE (SIBN) over the past year, gaining 94.3% versus a gain of 24.6%. Over five years, SIBN leads with a -16.4% price change compared with -88.8% for PACB. SI-BONE is the larger company by market cap ($845.3 million vs $714.9 million), about 1.2 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PACB | SIBN |
|---|---|---|
| Share price | $2.30 | $18.86 |
| Market cap | $714.91M | $845.28M |
| 1-day change | -15.44% | -1.26% |
| YTD return | +45.45% | -3.14% |
| 1-year return | +94.29% | +24.59% |
| 5-year return | -88.85% | -16.41% |
| EPS (TTM) | $-0.43 | $-0.34 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.44 | $21.89 |
| 52-week low | $1.07 | $11.48 |
| Distance from 52-week high | -33.14% | -13.84% |
| Analyst consensus | buy | strong_buy |
| Avg. price target upside | -6.09% | +33.72% |
| Average volume | 10.10M | 541.14K |
| Shares outstanding | 310.83M | 44.82M |
| Employees | 485 | 376 |
| Sector | Industrials | Health Care |
| Industry | Biotechnology: Laboratory Analytical Instruments | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- PACB has outperformed SIBN by 69.7 percentage points over the past year.
- The two companies sit in different sectors: Pacific Biosciences of California in Industrials and SI-BONE in Health Care.
About Pacific Biosciences of California
PACB stock →Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems.
Industrials · Biotechnology: Laboratory Analytical Instruments · 485 employees
About SI-BONE
SIBN stock →SI-BONE, Inc., a medical device company, develops procedural solutions for compromised bone, grounded in expertise in biomechanical design and anatomy-specific applications in the United States and internationally. It offers a series of patented titanium implants and the instruments used to implant them, as well as implantable bone products.
Health Care · Medical/Dental Instruments · 376 employees
PACB vs SIBN FAQ
Which is bigger, Pacific Biosciences of California or SI-BONE?
SI-BONE (SIBN) is larger, with a market capitalization of $845.28M compared with $714.91M for Pacific Biosciences of California (PACB).
Which stock has performed better over the past year, PACB or SIBN?
PACB returned +94.29% over the past 12 months, compared with +24.59% for SIBN (price return, excluding dividends). Past performance does not predict future results.
Are Pacific Biosciences of California and SI-BONE in the same industry?
No. Pacific Biosciences of California is in the Industrials sector, while SI-BONE is in Health Care.