MetaCap

Vaxcyte (PCVX) vs Qiagen N.V. (QGEN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Vaxcyte (PCVX) has outperformed Qiagen N.V. (QGEN) over the past year, gaining 59.9% versus a loss of 4.3%. Over five years, PCVX leads with a +174.3% price change compared with -16.0% for QGEN. Vaxcyte is the larger company by market cap ($9.96 billion vs $9.25 billion), about 1.1 times the size.

Qiagen N.V. pays a dividend yielding 0.81%, while Vaxcyte does not currently pay one.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PCVX+59.92%QGEN-4.29%
+82%+23%-36%
Oct 7, 20251 yearOct 7, 2026
PCVX+177.27%QGEN-15.02%
+401%+171%-58%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PCVX versus QGEN key metrics
MetricPCVXQGEN
Share price$66.96$44.79
Market cap$9.96B$9.25B
1-day change+0.39%-1.88%
YTD return+45.12%-0.40%
1-year return+59.92%-4.29%
5-year return+174.31%-15.95%
P/E ratio (TTM)—22.74
Forward P/E—17.14
EPS (TTM)$-7.62$1.97
Dividend yield0.00%0.81%
Annual dividend$0.00$0.363
Revenue (latest FY)—$2.09B
Revenue growth (YoY)—+5.65%
Net income (latest FY)$-766.63M$424.88M
Gross margin—62.18%
Operating margin—22.29%
Net margin—20.33%
52-week high$90.75$57.82
52-week low$39.87$32.53
Distance from 52-week high-26.21%-22.54%
Analyst consensusstrong_buybuy
Avg. price target upside+65.59%+5.54%
Average volume1.50M2.76M
Shares outstanding148.81M206.50M
Employees5075,500
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PCVX has outperformed QGEN by 64.2 percentage points over the past year.

About Vaxcyte

PCVX stock →

Vaxcyte, Inc., a clinical-stage vaccine innovation company, develops conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent carrier-sparing investigational pneumococcal conjugate vaccine (PCV) for the prevention of invasive pneumococcal disease (IPD) in infants.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 507 employees

About Qiagen N.V.

QGEN stock →

Qiagen N.V. provides sample to insight solutions that transform biological samples into molecular insights worldwide.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 5,500 employees

PCVX vs QGEN FAQ

Which is bigger, Vaxcyte or Qiagen N.V.?

Vaxcyte (PCVX) is larger, with a market capitalization of $9.96B compared with $9.25B for Qiagen N.V. (QGEN).

Which stock has performed better over the past year, PCVX or QGEN?

PCVX returned +59.92% over the past 12 months, compared with -4.29% for QGEN (price return, excluding dividends). Past performance does not predict future results.

Which pays a higher dividend, Vaxcyte or Qiagen N.V.?

Qiagen N.V. pays a dividend yielding 0.81%, while Vaxcyte does not currently pay a regular dividend.

Are Vaxcyte and Qiagen N.V. in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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