MetaCap

Precigen (PGEN) vs Supernus Pharmaceuticals (SUPN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Precigen (PGEN) has outperformed Supernus Pharmaceuticals (SUPN) over the past year, gaining 127.8% versus a loss of 10.4%. Over five years, PGEN leads with a +62.2% price change compared with +36.0% for SUPN. Precigen is the larger company by market cap ($2.72 billion vs $2.45 billion), about 1.1 times the size.

Supernus Pharmaceuticals converts more of its revenue into profit, with a net margin of -5.4% versus -2588.2%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PGEN+127.79%SUPN-10.44%
+167%+72%-23%
Oct 7, 20251 yearOct 7, 2026
PGEN+61.46%SUPN+63.25%
+119%+12%-95%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PGEN versus SUPN key metrics
MetricPGENSUPN
Share price$7.60$42.14
Market cap$2.72B$2.45B
1-day change+0.80%-2.11%
YTD return+80.38%-13.38%
1-year return+127.79%-10.44%
5-year return+62.15%+35.98%
Forward P/E—9.45
EPS (TTM)$-1.04$-1.92
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$9.68M$718.95M
Revenue growth (YoY)+146.73%+8.63%
Net income (latest FY)$-250.64M$-38.55M
Gross margin—89.63%
Operating margin-1141.13%-8.66%
Net margin-2588.21%-5.36%
52-week high$8.98$59.68
52-week low$2.99$40.51
Distance from 52-week high-15.37%-29.39%
Analyst consensusbuynone
Avg. price target upside+79.61%+46.54%
Average volume5.02M766.52K
Shares outstanding358.04M58.22M
Employees160778
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PGEN has outperformed SUPN by 138.2 percentage points over the past year.
  • Supernus Pharmaceuticals is more profitable, keeping -5.4 cents of every revenue dollar as net income versus -2588.2 cents for Precigen.
  • Precigen grew revenue faster in its latest fiscal year (+146.73% vs +8.63%).

About Precigen

PGEN stock →

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients.

Health Care · Biotechnology: Pharmaceutical Preparations · 160 employees

About Supernus Pharmaceuticals

SUPN stock →

Supernus Pharmaceuticals, Inc., a biopharmaceutical company, engages in the development and commercialization of products for the treatment of central nervous system (CNS) diseases in the United States. It offers Qelbree, a non-stimulant indicated for the treatment of attention-deficit hyperactivity disorder (ADHD); GOCOVRI for the treatment of dyskinesia and levodopa/carbidopa in patients with Parkinson's Disease (PD); Oxtellar XR, an extended-release oxcarbazepine product indicated for the monotherapy treatment of partial onset epilepsy seizures; and APOKYN for the acute and intermittent treatment of hypomobility or off episodes in patients with advanced PD.

Health Care · Biotechnology: Pharmaceutical Preparations · 778 employees

PGEN vs SUPN FAQ

Which is bigger, Precigen or Supernus Pharmaceuticals?

Precigen (PGEN) is larger, with a market capitalization of $2.72B compared with $2.45B for Supernus Pharmaceuticals (SUPN).

Which stock has performed better over the past year, PGEN or SUPN?

PGEN returned +127.79% over the past 12 months, compared with -10.44% for SUPN (price return, excluding dividends). Past performance does not predict future results.

Are Precigen and Supernus Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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