Pliant Therapeutics (PLRX) vs Xilio Therapeutics (XLO)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Xilio Therapeutics (XLO) has outperformed Pliant Therapeutics (PLRX) over the past year, losing 21.7% versus a loss of 33.1%. Pliant Therapeutics is the larger company by market cap ($61.3 million vs $59.3 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PLRX | XLO |
|---|---|---|
| Share price | $0.99 | $9.01 |
| Market cap | $61.30M | $59.29M |
| 1-day change | -3.88% | +0.11% |
| YTD return | -18.85% | +0.56% |
| 1-year return | -33.11% | -21.71% |
| 5-year return | -94.50% | — |
| EPS (TTM) | $-1.44 | $-0.60 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $1.95 | $12.59 |
| 52-week low | $0.97 | $6.47 |
| Distance from 52-week high | -49.23% | -28.41% |
| Average volume | 488.25K | 20.06K |
| Shares outstanding | 61.92M | 6.58M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- XLO has outperformed PLRX by 11.4 percentage points over the past year.
PLRX vs XLO FAQ
Which is bigger, Pliant Therapeutics or Xilio Therapeutics?
Pliant Therapeutics (PLRX) is larger, with a market capitalization of $61.30M compared with $59.29M for Xilio Therapeutics (XLO).
Which stock has performed better over the past year, PLRX or XLO?
XLO returned -21.71% over the past 12 months, compared with -33.11% for PLRX (price return, excluding dividends). Past performance does not predict future results.
Are Pliant Therapeutics and Xilio Therapeutics in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.