MetaCap

Polaryx Therapeutics (PLYX) vs Unicycive Therapeutics (UNCY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 18, 2026.

Summary

Polaryx Therapeutics is the larger company by market cap ($93.7 million vs $92.0 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PLYX-94.63%UNCY-47.91%
+39%-31%-101%
Feb 2, 20261 yearOct 16, 2026
PLYX-78.90%UNCY-49.78%
+29%-28%-84%
Feb 2, 20265 yearsOct 12, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PLYX versus UNCY key metrics
MetricPLYXUNCY
Share price$1.88$3.36
Market cap$93.71M$92.04M
1-day change-3.59%-6.41%
YTD return—-41.77%
1-year return—-28.66%
5-year return—-86.77%
Forward P/E—1.99
EPS (TTM)$-0.14$-1.75
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Net income (latest FY)$-8.98M$-26.55M
52-week high$48.91$8.74
52-week low$1.85$3.35
Distance from 52-week high-96.16%-61.56%
Analyst consensusnonestrong_buy
Avg. price target upside+298.94%+745.24%
Average volume70.79K845.87K
Shares outstanding49.85M27.39M
Employees221
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Polaryx Therapeutics

PLYX stock →

Polaryx Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of disease-modifying therapies for rare and pediatric lysosomal storage disorders in the United States. Its pipeline includes PLX-100, a preclinical stage orally administrable combination therapy; PLX-200, a repurposed oral small molecule for the treatment of LSDs; PLX-300, a preclinical stage orally administrable combination therapy; and PLX-400, a preclinical stage novel gene therapy candidate.

Health Care · Biotechnology: Pharmaceutical Preparations · 2 employees

About Unicycive Therapeutics

UNCY stock →

Unicycive Therapeutics, Inc., a clinical-stage biotechnology company, identifies, develops, and commercializes therapies for the treatment of kidney diseases in the United States. It develops oxylanthanum carbonate, a lanthanum-based phosphate binding agent, which is for the treatment of hyperphosphatemia in patients with chronic kidney disease on dialysis; and UNI-494, a nicotinamide ester derivative and a selective ATP-sensitive mitochondrial potassium channel activator, which is in Phase I clinical trial for the treatment of acute kidney injury and pre-clinical stage for the treatment of chronic kidney disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 21 employees

PLYX vs UNCY FAQ

Which is bigger, Polaryx Therapeutics or Unicycive Therapeutics?

Polaryx Therapeutics (PLYX) is larger, with a market capitalization of $93.71M compared with $92.04M for Unicycive Therapeutics (UNCY).

Are Polaryx Therapeutics and Unicycive Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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