MetaCap

Prelude Therapeutics (PRLD) vs Rocket Pharmaceuticals (RCKT)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Prelude Therapeutics (PRLD) has outperformed Rocket Pharmaceuticals (RCKT) over the past year, gaining 173.2% versus a loss of 22.4%. Over five years, PRLD leads with a -76.1% price change compared with -90.6% for RCKT. Prelude Therapeutics is the larger company by market cap ($309.6 million vs $288.7 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PRLD+173.24%RCKT-22.42%
+387%+170%-47%
Oct 8, 20251 yearOct 8, 2026
PRLD-75.55%RCKT-90.89%
+30%-36%-102%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PRLD versus RCKT key metrics
MetricPRLDRCKT
Share price$3.88$2.63
Market cap$309.64M$288.71M
1-day change+1.31%+3.75%
YTD return+33.79%-25.07%
1-year return+173.24%-22.42%
5-year return-76.14%-90.58%
EPS (TTM)$-0.73$-0.17
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$6.83$5.45
52-week low$1.15$2.42
Distance from 52-week high-43.19%-51.74%
Analyst consensusstrong_buybuy
Avg. price target upside+137.11%+223.19%
Average volume479.23K1.66M
Shares outstanding65.08M109.77M
Employees79202
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PRLD has outperformed RCKT by 195.7 percentage points over the past year.

About Prelude Therapeutics

PRLD stock →

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET.

Health Care · Biotechnology: Pharmaceutical Preparations · 79 employees

About Rocket Pharmaceuticals

RCKT stock →

Rocket Pharmaceuticals, Inc., together with its subsidiaries, operates as a late-stage biotechnology company that focuses on developing, manufacturing, and selling of genetic therapies for rare and devastating diseases in the United States. It develops in vivo adeno-associated viral (AAV) programs, which include programs for Danon disease (DD), a multi-organ lysosomal-associated disorder leading to early death due to heart failure (RP-A501), which is in Phase 2 trial; Plakophilin-2 Arrhythmogenic Cardiomyopathy (PKP2-ACM), an inheritable cardiac disorder that is characterized by a progressive loss of cardiac muscle mass, severe right ventricular dilation, dysplasia, fibrofatty replacement of the myocardium and a high propensity to arrhythmias and sudden death (RP-A601), which is in phase 1; and BAG3 Dilated Cardiomyopathy (BAG3-DCM), which is a form of cardiomyopathy and is characterized by progressive thinning of the walls of the heart, which is in preclinical stage.

Health Care · Biotechnology: Pharmaceutical Preparations · 202 employees

PRLD vs RCKT FAQ

Which is bigger, Prelude Therapeutics or Rocket Pharmaceuticals?

Prelude Therapeutics (PRLD) is larger, with a market capitalization of $309.64M compared with $288.71M for Rocket Pharmaceuticals (RCKT).

Which stock has performed better over the past year, PRLD or RCKT?

PRLD returned +173.24% over the past 12 months, compared with -22.42% for RCKT (price return, excluding dividends). Past performance does not predict future results.

Are Prelude Therapeutics and Rocket Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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