ProQR Therapeutics N.V. (PRQR) vs SIGA Technologies (SIGA)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
ProQR Therapeutics N.V. (PRQR) has outperformed SIGA Technologies (SIGA) over the past year, losing 33.5% versus a loss of 60.4%. Over five years, SIGA leads with a -53.9% price change compared with -80.1% for PRQR. SIGA Technologies is the larger company by market cap ($235.7 million vs $221.6 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PRQR | SIGA |
|---|---|---|
| Share price | $1.57 | $3.28 |
| Market cap | $221.56M | $235.67M |
| 1-day change | -3.68% | +0.61% |
| YTD return | -22.28% | -46.32% |
| 1-year return | -33.47% | -60.39% |
| 5-year return | -80.08% | -53.87% |
| Forward P/E | — | 3.04 |
| EPS (TTM) | $-0.45 | $-0.04 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.10 | $8.55 |
| 52-week low | $1.33 | $2.83 |
| Distance from 52-week high | -49.35% | -61.64% |
| Analyst consensus | strong_buy | none |
| Avg. price target upside | +395.54% | — |
| Average volume | 796.41K | 726.75K |
| Shares outstanding | 141.12M | 71.85M |
| Employees | 186 | 49 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- PRQR has outperformed SIGA by 26.9 percentage points over the past year.
About ProQR Therapeutics N.V.
PRQR stock →ProQR Therapeutics N.V., a clinical-stage biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company develops an RNA editing platform through its Axiomer RNA editing technology for genetic disorders with unmet needs.
Health Care · Biotechnology: Pharmaceutical Preparations · 186 employees
About SIGA Technologies
SIGA stock →SIGA Technologies, Inc., a commercial-stage pharmaceutical company, focuses on the health security market in the United States. The company's lead product is TPOXX, an antiviral drug for the treatment of human smallpox disease caused by variola virus.
Health Care · Biotechnology: Pharmaceutical Preparations · 49 employees
PRQR vs SIGA FAQ
Which is bigger, ProQR Therapeutics N.V. or SIGA Technologies?
SIGA Technologies (SIGA) is larger, with a market capitalization of $235.67M compared with $221.56M for ProQR Therapeutics N.V. (PRQR).
Which stock has performed better over the past year, PRQR or SIGA?
PRQR returned -33.47% over the past 12 months, compared with -60.39% for SIGA (price return, excluding dividends). Past performance does not predict future results.
Are ProQR Therapeutics N.V. and SIGA Technologies in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.