Personalis (PSNL) vs Trupanion (TRUP)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Personalis (PSNL) has outperformed Trupanion (TRUP) over the past year, gaining 85.0% versus a loss of 41.8%. Over five years, PSNL leads with a -19.8% price change compared with -73.0% for TRUP. Personalis is the larger company by market cap ($1.72 billion vs $1.13 billion), about 1.5 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PSNL | TRUP |
|---|---|---|
| Share price | $16.06 | $25.82 |
| Market cap | $1.72B | $1.13B |
| 1-day change | +0.37% | +4.83% |
| YTD return | +101.76% | -34.09% |
| 1-year return | +85.02% | -41.77% |
| 5-year return | -19.76% | -72.98% |
| P/E ratio (TTM) | — | 48.72 |
| Forward P/E | — | 6.06 |
| EPS (TTM) | $-1.09 | $0.53 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $18.89 | $46.98 |
| 52-week low | $4.96 | $21.16 |
| Distance from 52-week high | -14.98% | -45.04% |
| Analyst consensus | hold | buy |
| Avg. price target upside | -5.54% | +32.65% |
| Average volume | 3.59M | 470.46K |
| Shares outstanding | 106.80M | 43.62M |
| Employees | 259 | 1,121 |
| Sector | Healthcare | Health Care |
| Industry | Diagnostics & Research | Medical Specialities |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- PSNL has outperformed TRUP by 126.8 percentage points over the past year.
- The two companies sit in different sectors: Personalis in Healthcare and Trupanion in Health Care.
About Personalis
PSNL stock →Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally.
Healthcare · Diagnostics & Research · 259 employees
About Trupanion
TRUP stock →Trupanion, Inc., together with its subsidiaries, provides medical insurance for cats and dogs on subscription basis in the United States, Canada, and Continental Europe. The company operates in two segments, Subscription Business and Other Business.
Health Care · Medical Specialities · 1,121 employees
PSNL vs TRUP FAQ
Which is bigger, Personalis or Trupanion?
Personalis (PSNL) is larger, with a market capitalization of $1.72B compared with $1.13B for Trupanion (TRUP).
Which stock has performed better over the past year, PSNL or TRUP?
PSNL returned +85.02% over the past 12 months, compared with -41.77% for TRUP (price return, excluding dividends). Past performance does not predict future results.
Are Personalis and Trupanion in the same industry?
No. Personalis is in the Healthcare sector, while Trupanion is in Health Care.