Personalis (PSNL) vs Waters (WAT)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Personalis (PSNL) has outperformed Waters (WAT) over the past year, gaining 85.0% versus a gain of 31.0%. Over five years, WAT leads with a +24.5% price change compared with -19.5% for PSNL. Waters is the larger company by market cap ($42.13 billion vs $1.72 billion), about 24.6 times the size.
Waters converts more of its revenue into profit, with a net margin of 20.3% versus -116.7%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | PSNL | WAT |
|---|---|---|
| Share price | $16.06 | $429.13 |
| Market cap | $1.72B | $42.13B |
| 1-day change | +0.37% | -1.57% |
| YTD return | +101.76% | +12.98% |
| 1-year return | +85.02% | +30.97% |
| 5-year return | -19.46% | +24.49% |
| P/E ratio (TTM) | — | 108.64 |
| Forward P/E | — | 25.95 |
| EPS (TTM) | $-1.09 | $3.95 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $69.65M | $3.17B |
| Revenue growth (YoY) | -17.69% | +6.99% |
| Net income (latest FY) | $-81.27M | $642.63M |
| Gross margin | 22.65% | 59.28% |
| Operating margin | -126.43% | 25.36% |
| Net margin | -116.69% | 20.30% |
| 52-week high | $18.89 | $454.54 |
| 52-week low | $4.96 | $282.77 |
| Distance from 52-week high | -14.98% | -5.59% |
| Analyst consensus | hold | buy |
| Avg. price target upside | -5.54% | +6.42% |
| Average volume | 3.59M | 777.61K |
| Shares outstanding | 106.80M | 98.19M |
| Employees | 259 | 16,000 |
| Sector | Healthcare | Healthcare |
| Industry | Diagnostics & Research | Diagnostics & Research |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Waters is about 24.6 times larger than Personalis by market value ($42.13B vs $1.72B).
- PSNL has outperformed WAT by 54.1 percentage points over the past year.
- Waters is more profitable, keeping 20.3 cents of every revenue dollar as net income versus -116.7 cents for Personalis.
- Waters grew revenue faster in its latest fiscal year (+6.99% vs -17.69%).
About Personalis
PSNL stock →Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally.
Healthcare · Diagnostics & Research · 259 employees
About Waters
WAT stock →Waters Corporation provides analytical workflow solutions in Asia, the Americas, and Europe. The company operates through two segments, Waters and TA.
Healthcare · Diagnostics & Research · 16,000 employees
PSNL vs WAT FAQ
Which is bigger, Personalis or Waters?
Waters (WAT) is larger, with a market capitalization of $42.13B compared with $1.72B for Personalis (PSNL).
Which stock has performed better over the past year, PSNL or WAT?
PSNL returned +85.02% over the past 12 months, compared with +30.97% for WAT (price return, excluding dividends). Past performance does not predict future results.
Are Personalis and Waters in the same industry?
Yes. Both are classified in the Diagnostics & Research industry within the Healthcare sector.