MetaCap

Palvella Therapeutics (PVLA) vs Recursion Pharmaceuticals (RXRX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

Palvella Therapeutics (PVLA) has outperformed Recursion Pharmaceuticals (RXRX) over the past year, gaining 98.0% versus a loss of 26.2%. Over five years, PVLA leads with a -61.5% price change compared with -77.1% for RXRX. Recursion Pharmaceuticals is the larger company by market cap ($2.34 billion vs $2.00 billion), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

PVLA+97.99%RXRX-26.23%
+134%+37%-61%
Oct 9, 20251 yearOct 9, 2026
PVLA-63.48%RXRX-76.66%
+11%-46%-103%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

PVLA versus RXRX key metrics
MetricPVLARXRX
Share price$138.77$4.36
Market cap$2.00B$2.34B
1-day change+5.66%+10.38%
YTD return+32.58%+6.60%
1-year return+97.99%-26.23%
5-year return-61.54%-77.10%
EPS (TTM)$-4.85$-1.10
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$74.68M
Revenue growth (YoY)—+26.92%
Net income (latest FY)$-41.72M$-644.76M
Gross margin—4.99%
Operating margin—-867.87%
Net margin—-863.35%
52-week high$161.38$7.18
52-week low$66.58$2.77
Distance from 52-week high-14.01%-39.28%
Analyst consensusnonenone
Avg. price target upside+66.12%+65.60%
Average volume210.72K20.93M
Shares outstanding14.41M535.34M
Employees29600
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PVLA has outperformed RXRX by 124.2 percentage points over the past year.

About Palvella Therapeutics

PVLA stock →

Palvella Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel therapies to treat patients serious and rare genetic skin diseases. The company's lead product candidate is QTORIN rapamycin, a novel, 3.9% anhydrous topical gel that is in Phase 3 clinical trial for the treatment of microcystic lymphatic malformations, as well as in Phase 2 clinical trial to treat cutaneous venous malformations.

Health Care · Biotechnology: Pharmaceutical Preparations · 29 employees

About Recursion Pharmaceuticals

RXRX stock →

Recursion Pharmaceuticals, Inc., a clinical-stage biotechnology company, engages in the decoding biology and chemistry by integrating technological innovations across biology, chemistry, automation, data science, and engineering to industrialize drug discovery in the United States and the United Kingdom. The company develops REC-4881, which is in Phase 1b/2 clinical trial to treat familial adenomatous polyposis; REC-617, which is in Phase 1/2 clinical trial to treat advanced solid tumors; REC-1245, which is in Phase 1/2 clinical trial to treat biomarker-enriched solid tumors and lymphoma; REC-3565 that is in Phase 1/2 for the treatment of relapsed or refractory B-cell malignancies; and REC-4539, a reversible, CNS penetrant, orally bioavailable, and potential best-in-class inhibitor of LSD1 for the treatment of solid tumors and hematology oncology.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 600 employees

PVLA vs RXRX FAQ

Which is bigger, Palvella Therapeutics or Recursion Pharmaceuticals?

Recursion Pharmaceuticals (RXRX) is larger, with a market capitalization of $2.34B compared with $2.00B for Palvella Therapeutics (PVLA).

Which stock has performed better over the past year, PVLA or RXRX?

PVLA returned +97.99% over the past 12 months, compared with -26.23% for RXRX (price return, excluding dividends). Past performance does not predict future results.

Are Palvella Therapeutics and Recursion Pharmaceuticals in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: Pharmaceutical Preparations for Palvella Therapeutics and Biotechnology: Biological Products (No Diagnostic Substances) for Recursion Pharmaceuticals.

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