MetaCap

QuidelOrtho (QDEL) vs SI-BONE (SIBN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

SI-BONE (SIBN) has outperformed QuidelOrtho (QDEL) over the past year, gaining 24.0% versus a loss of 52.2%. Over five years, SIBN leads with a -17.5% price change compared with -89.5% for QDEL. QuidelOrtho is the larger company by market cap ($920.3 million vs $868.1 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

QDEL-55.77%SIBN+19.97%
+41%-14%-70%
Oct 9, 20251 yearOct 8, 2026
QDEL-90.28%SIBN-12.77%
+40%-30%-99%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

QDEL versus SIBN key metrics
MetricQDELSIBN
Share price$13.42$19.37
Market cap$920.28M$868.14M
1-day change+8.14%+2.70%
YTD return-53.01%-4.36%
1-year return-52.17%+24.00%
5-year return-89.54%-17.46%
Forward P/E9.31—
EPS (TTM)$-15.39$-0.34
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$35.58$21.89
52-week low$9.92$11.48
Distance from 52-week high-62.28%-11.51%
Analyst consensusholdstrong_buy
Avg. price target upside+9.31%+30.20%
Average volume1.51M543.48K
Shares outstanding68.58M44.82M
Employees6,500376
SectorHealth CareHealth Care
IndustryBiotechnology: In Vitro & In Vivo Diagnostic SubstancesMedical/Dental Instruments

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • SIBN has outperformed QDEL by 76.2 percentage points over the past year.

About QuidelOrtho

QDEL stock →

QuidelOrtho Corporation provides diagnostic testing solutions. The company operates through Labs, Transfusion Medicine, Point of Care, and Molecular Diagnostics business units.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 6,500 employees

About SI-BONE

SIBN stock →

SI-BONE, Inc., a medical device company, develops procedural solutions for compromised bone, grounded in expertise in biomechanical design and anatomy-specific applications in the United States and internationally. It offers a series of patented titanium implants and the instruments used to implant them, as well as implantable bone products.

Health Care · Medical/Dental Instruments · 376 employees

QDEL vs SIBN FAQ

Which is bigger, QuidelOrtho or SI-BONE?

QuidelOrtho (QDEL) is larger, with a market capitalization of $920.28M compared with $868.14M for SI-BONE (SIBN).

Which stock has performed better over the past year, QDEL or SIBN?

SIBN returned +24.00% over the past 12 months, compared with -52.17% for QDEL (price return, excluding dividends). Past performance does not predict future results.

Are QuidelOrtho and SI-BONE in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: In Vitro & In Vivo Diagnostic Substances for QuidelOrtho and Medical/Dental Instruments for SI-BONE.

More comparisons