MetaCap

Rafael (RFL) vs Rallybio (RLYB)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Rallybio (RLYB) has outperformed Rafael (RFL) over the past year, gaining 268.7% versus a gain of 9.6%. Over five years, RLYB leads with a -86.3% price change compared with -95.1% for RFL. Rallybio is the larger company by market cap ($90.4 million vs $83.2 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

RFL+9.63%RLYB+268.71%
+288%+130%-28%
Oct 8, 20251 yearOct 8, 2026
RFL-95.29%RLYB-88.02%
+15%-45%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

RFL versus RLYB key metrics
MetricRFLRLYB
Share price$1.60$17.02
Market cap$83.20M$90.42M
1-day change+8.11%+0.18%
YTD return+25.42%+209.58%
1-year return+9.63%+268.71%
5-year return-95.09%-86.32%
P/E ratio (TTM)—2.12
EPS (TTM)$-0.72$8.01
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.96$17.57
52-week low$1.12$3.67
Distance from 52-week high-59.60%-3.15%
Average volume159.84K21.33K
Shares outstanding51.21M5.31M
Employees217
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • RLYB has outperformed RFL by 259.1 percentage points over the past year.

About Rafael

RFL stock →

Rafael Holdings, Inc. primarily engages in holding interests in clinical and early-stage pharmaceutical companies, and medical devices in the United States and Israel.

Health Care · Biotechnology: Pharmaceutical Preparations · 21 employees

About Rallybio

RLYB stock →

Rallybio Corporation, a clinical-stage biotechnology company, engages in the development and commercialization of life-transforming therapies for patients suffering from severe and rare diseases. Its lead product candidate is the RLYB116, an inhibitor of complement component 5 (C5) to treat several diseases of complement dysregulation which has completed phase 1 trial; and RLYB332, a preclinical antibody, for the treatment of severe anemia with ineffective erythropoiesis and iron overload.

Health Care · Biotechnology: Pharmaceutical Preparations · 7 employees

RFL vs RLYB FAQ

Which is bigger, Rafael or Rallybio?

Rallybio (RLYB) is larger, with a market capitalization of $90.42M compared with $83.20M for Rafael (RFL).

Which stock has performed better over the past year, RFL or RLYB?

RLYB returned +268.71% over the past 12 months, compared with +9.63% for RFL (price return, excluding dividends). Past performance does not predict future results.

Are Rafael and Rallybio in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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