MetaCap

Royalty Pharma (RPRX) vs United Therapeutics (UTHR)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Royalty Pharma (RPRX) has outperformed United Therapeutics (UTHR) over the past year, gaining 57.2% versus a gain of 18.7%. Over five years, UTHR leads with a +184.8% price change compared with +47.9% for RPRX. Royalty Pharma is the larger company by market cap ($32.48 billion vs $22.85 billion), about 1.4 times the size, while United Therapeutics is growing revenue faster (+10.6% vs +5.1%).

On valuation, Royalty Pharma trades at a lower forward P/E (9.8x vs 17.0x for United Therapeutics). Royalty Pharma pays a dividend yielding 1.62%, while United Therapeutics does not currently pay one. United Therapeutics converts more of its revenue into profit, with a net margin of 41.9% versus 32.4%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

RPRX+57.23%UTHR+19.30%
+81%+34%-13%
Oct 7, 20251 yearOct 7, 2026
RPRX+59.93%UTHR+172.69%
+213%+86%-42%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

RPRX versus UTHR key metrics
MetricRPRXUTHR
Share price$56.21$532.78
Market cap$32.48B$22.85B
1-day change-0.97%-2.24%
YTD return+46.89%+9.34%
1-year return+57.23%+18.68%
5-year return+47.85%+184.80%
P/E ratio (TTM)29.9019.08
Forward P/E9.8017.04
EPS (TTM)$1.88$27.92
Dividend yield1.62%0.00%
Annual dividend$0.91$0.00
Revenue (latest FY)$2.38B$3.18B
Revenue growth (YoY)+5.06%+10.61%
Net income (latest FY)$770.95M$1.33B
Gross margin—87.92%
Operating margin65.58%46.89%
Net margin32.42%41.94%
52-week high$64.38$609.35
52-week low$35.23$409.07
Distance from 52-week high-12.69%-12.57%
Analyst consensusstrong_buybuy
Avg. price target upside+16.31%+21.93%
Average volume2.93M655.10K
Shares outstanding445.28M42.89M
Employees1001,400
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • RPRX has outperformed UTHR by 38.6 percentage points over the past year.
  • Royalty Pharma trades at a higher earnings multiple (29.9x vs 19.1x trailing P/E).
  • Royalty Pharma offers a meaningfully higher dividend yield (1.62% vs 0.00%).
  • United Therapeutics is more profitable, keeping 41.9 cents of every revenue dollar as net income versus 32.4 cents for Royalty Pharma.
  • United Therapeutics grew revenue faster in its latest fiscal year (+10.61% vs +5.06%).

About Royalty Pharma

RPRX stock →

Royalty Pharma plc operates as a buyer of biopharmaceutical royalties and a funder of innovation in the biopharmaceutical industry in the United States. Its portfolio consists of royalties on approximately 35 marketed therapies and 20 development-stage product candidates that address various therapeutic areas, such as rare disease, oncology, neuroscience, infectious disease, hematology, and diabetes.

Health Care · Biotechnology: Pharmaceutical Preparations · 100 employees

About United Therapeutics

UTHR stock →

United Therapeutics Corporation engages in the development and commercialization of products to address the unmet medical needs of patients with chronic and life-threatening diseases in the United States and internationally. It offers Tyvaso DPI, an inhaled dry powder via pre-filled and single-use cartridges; Nebulized Tyvaso, an inhaled solution via ultrasonic nebulizer; Remodulin (treprostinil) injection to treat patients with pulmonary arterial hypertension to diminish symptoms associated with exercise; Orenitram, a tablet dosage form of treprostinil, to delay disease progression and improve exercise capacity in PAH patients; and Adcirca, an oral PDE-5 inhibitor to enhance the exercise ability in PAH patients.

Health Care · Biotechnology: Pharmaceutical Preparations · 1,400 employees

RPRX vs UTHR FAQ

Which is bigger, Royalty Pharma or United Therapeutics?

Royalty Pharma (RPRX) is larger, with a market capitalization of $32.48B compared with $22.85B for United Therapeutics (UTHR).

Which stock has performed better over the past year, RPRX or UTHR?

RPRX returned +57.23% over the past 12 months, compared with +18.68% for UTHR (price return, excluding dividends). Past performance does not predict future results.

Which has the lower P/E ratio, RPRX or UTHR?

UTHR has the lower trailing P/E at 19.1, versus 29.9 for RPRX. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.

Which pays a higher dividend, Royalty Pharma or United Therapeutics?

Royalty Pharma pays a dividend yielding 1.62%, while United Therapeutics does not currently pay a regular dividend.

Are Royalty Pharma and United Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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