MetaCap

SAB Biotherapeutics (SABS) vs Vanda Pharmaceuticals (VNDA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

SAB Biotherapeutics (SABS) has outperformed Vanda Pharmaceuticals (VNDA) over the past year, gaining 23.5% versus a loss of 16.1%. Over five years, VNDA leads with a -75.2% price change compared with -97.1% for SABS. Vanda Pharmaceuticals is the larger company by market cap ($276.3 million vs $271.1 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

SABS+23.50%VNDA-17.03%
+102%+38%-27%
Oct 8, 20251 yearOct 8, 2026
SABS-97.13%VNDA-74.74%
+15%-45%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

SABS versus VNDA key metrics
MetricSABSVNDA
Share price$2.98$4.57
Market cap$271.14M$276.31M
1-day change+3.11%+0.88%
YTD return-22.73%-48.19%
1-year return+23.50%-16.15%
5-year return-97.14%-75.18%
Forward P/E—22.85
EPS (TTM)$-1.29$-4.63
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$5.15$9.94
52-week low$2.10$4.27
Distance from 52-week high-42.14%-54.02%
Analyst consensusnonestrong_buy
Avg. price target upside+290.60%+157.11%
Average volume497.66K974.13K
Shares outstanding90.99M60.46M
Employees86533
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • SABS has outperformed VNDA by 39.7 percentage points over the past year.

About SAB Biotherapeutics

SABS stock →

SAB Biotherapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development of human polyclonal immunotherapeutic antibodies to address immune system disorders and infectious diseases in the United States. Its lead product candidate is SAB-142, a potentially disease-modifying and redosable immunotherapy in clinical development for the treatment of autoimmune type 1 diabetes in Phase 2b clinical trials.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 86 employees

About Vanda Pharmaceuticals

VNDA stock →

Vanda Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of therapies to address high unmet medical needs worldwide. The company's commercial portfolio includes Fanapt for the acute treatment of manic or mixed episodes associated with bipolar I disorder and the treatment of schizophrenia; HETLIOZ to treat non-24-hour sleep-wake disorders and nighttime sleep disturbances; PONVORY to treat relapsing forms of multiple sclerosis; and NEREUSTM for preventing vomiting induced by motion.

Health Care · Biotechnology: Pharmaceutical Preparations · 533 employees

SABS vs VNDA FAQ

Which is bigger, SAB Biotherapeutics or Vanda Pharmaceuticals?

Vanda Pharmaceuticals (VNDA) is larger, with a market capitalization of $276.31M compared with $271.14M for SAB Biotherapeutics (SABS).

Which stock has performed better over the past year, SABS or VNDA?

SABS returned +23.50% over the past 12 months, compared with -16.15% for VNDA (price return, excluding dividends). Past performance does not predict future results.

Are SAB Biotherapeutics and Vanda Pharmaceuticals in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: Biological Products (No Diagnostic Substances) for SAB Biotherapeutics and Biotechnology: Pharmaceutical Preparations for Vanda Pharmaceuticals.

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