Shuttle Pharmaceuticals (SHPH) vs TherapeuticsMD (TXMD)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
TherapeuticsMD (TXMD) has outperformed Shuttle Pharmaceuticals (SHPH) over the past year, gaining 89.6% versus a loss of 87.4%. Shuttle Pharmaceuticals is the larger company by market cap ($26.4 million vs $23.3 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | SHPH | TXMD |
|---|---|---|
| Share price | $5.55 | $2.01 |
| Market cap | $26.44M | $23.26M |
| 1-day change | +17.83% | +0.50% |
| YTD return | -69.17% | +23.31% |
| 1-year return | -87.36% | +89.62% |
| 5-year return | — | -94.42% |
| Forward P/E | — | 5.74 |
| EPS (TTM) | $-16.87 | $-0.04 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $55.90 | $2.95 |
| 52-week low | $2.58 | $1.03 |
| Distance from 52-week high | -90.07% | -31.86% |
| Average volume | 1.36M | 23.94K |
| Shares outstanding | 4.76M | 11.57M |
| Employees | 2 | 1 |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TXMD has outperformed SHPH by 177.0 percentage points over the past year.
About Shuttle Pharmaceuticals
SHPH stock →Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to treat cancers. It owns a pharmaceutical software artificial intelligence (AI) driven platform for molecular discovery and early-stage drug development.
Healthcare · Drug Manufacturers - Specialty & Generic · 2 employees
About TherapeuticsMD
TXMD stock →TherapeuticsMD, Inc. operates as a pharmaceutical royalty company in the United States and internationally.
Healthcare · Drug Manufacturers - Specialty & Generic · 1 employees
SHPH vs TXMD FAQ
Which is bigger, Shuttle Pharmaceuticals or TherapeuticsMD?
Shuttle Pharmaceuticals (SHPH) is larger, with a market capitalization of $26.44M compared with $23.26M for TherapeuticsMD (TXMD).
Which stock has performed better over the past year, SHPH or TXMD?
TXMD returned +89.62% over the past 12 months, compared with -87.36% for SHPH (price return, excluding dividends). Past performance does not predict future results.
Are Shuttle Pharmaceuticals and TherapeuticsMD in the same industry?
Yes. Both are classified in the Drug Manufacturers - Specialty & Generic industry within the Healthcare sector.