MetaCap

SELLAS Life Sciences Group (SLS) vs Supernus Pharmaceuticals (SUPN)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

SELLAS Life Sciences Group (SLS) has outperformed Supernus Pharmaceuticals (SUPN) over the past year, gaining 495.3% versus a loss of 10.4%. Over five years, SUPN leads with a +36.0% price change compared with +28.1% for SLS. Supernus Pharmaceuticals is the larger company by market cap ($2.51 billion vs $2.28 billion), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

SLS+495.26%SUPN-10.44%
+751%+343%-64%
Oct 7, 20251 yearOct 7, 2026
SLS+30.30%SUPN+63.25%
+119%+7%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

SLS versus SUPN key metrics
MetricSLSSUPN
Share price$11.31$43.05
Market cap$2.28B$2.51B
1-day change-0.26%+0.51%
YTD return+200.00%-13.38%
1-year return+495.26%-10.44%
5-year return+28.09%+35.98%
Forward P/E—9.65
EPS (TTM)$-0.21$-1.92
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$718.95M
Revenue growth (YoY)—+8.63%
Net income (latest FY)—$-38.55M
Gross margin—89.63%
Operating margin—-8.66%
Net margin—-5.36%
52-week high$15.88$59.68
52-week low$1.39$40.51
Distance from 52-week high-28.78%-27.87%
Analyst consensusnonenone
Avg. price target upside+187.36%+43.44%
Average volume6.56M766.52K
Shares outstanding201.95M58.22M
Employees13778
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • SLS has outperformed SUPN by 505.7 percentage points over the past year.

About SELLAS Life Sciences Group

SLS stock →

SELLAS Life Sciences Group, Inc., a late-stage clinical biopharmaceutical company, focuses on the development of novel therapeutics for various cancer indications in the United States. The company's lead product candidate is galinpepimut-S (GPS), a peptide immunotherapy directed against the Wilms tumor 1, antigen; and SLS009 (tambiciclib), a selective small molecule cyclin-dependent kinase 9, or CDK9, inhibitor.

Health Care · Biotechnology: Pharmaceutical Preparations · 13 employees

About Supernus Pharmaceuticals

SUPN stock →

Supernus Pharmaceuticals, Inc., a biopharmaceutical company, engages in the development and commercialization of products for the treatment of central nervous system (CNS) diseases in the United States. It offers Qelbree, a non-stimulant indicated for the treatment of attention-deficit hyperactivity disorder (ADHD); GOCOVRI for the treatment of dyskinesia and levodopa/carbidopa in patients with Parkinson's Disease (PD); Oxtellar XR, an extended-release oxcarbazepine product indicated for the monotherapy treatment of partial onset epilepsy seizures; and APOKYN for the acute and intermittent treatment of hypomobility or off episodes in patients with advanced PD.

Health Care · Biotechnology: Pharmaceutical Preparations · 778 employees

SLS vs SUPN FAQ

Which is bigger, SELLAS Life Sciences Group or Supernus Pharmaceuticals?

Supernus Pharmaceuticals (SUPN) is larger, with a market capitalization of $2.51B compared with $2.28B for SELLAS Life Sciences Group (SLS).

Which stock has performed better over the past year, SLS or SUPN?

SLS returned +495.26% over the past 12 months, compared with -10.44% for SUPN (price return, excluding dividends). Past performance does not predict future results.

Are SELLAS Life Sciences Group and Supernus Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

More comparisons