Spero Therapeutics (SPRO) vs Verrica Pharmaceuticals (VRCA)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Verrica Pharmaceuticals (VRCA) has outperformed Spero Therapeutics (SPRO) over the past year, losing 10.2% versus a loss of 45.8%. Over five years, SPRO leads with a -93.1% price change compared with -96.9% for VRCA. Verrica Pharmaceuticals is the larger company by market cap ($71.8 million vs $66.4 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | SPRO | VRCA |
|---|---|---|
| Share price | $1.14 | $4.18 |
| Market cap | $66.39M | $71.81M |
| 1-day change | -2.56% | +0.97% |
| YTD return | -49.79% | -50.18% |
| 1-year return | -45.83% | -10.20% |
| 5-year return | -93.13% | -96.90% |
| P/E ratio (TTM) | 8.14 | — |
| EPS (TTM) | $0.14 | $-1.75 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.08 | $9.82 |
| 52-week low | $1.08 | $3.28 |
| Distance from 52-week high | -62.99% | -57.44% |
| Average volume | 1.20M | 62.53K |
| Shares outstanding | 58.23M | 17.18M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- VRCA has outperformed SPRO by 35.6 percentage points over the past year.
SPRO vs VRCA FAQ
Which is bigger, Spero Therapeutics or Verrica Pharmaceuticals?
Verrica Pharmaceuticals (VRCA) is larger, with a market capitalization of $71.81M compared with $66.39M for Spero Therapeutics (SPRO).
Which stock has performed better over the past year, SPRO or VRCA?
VRCA returned -10.20% over the past 12 months, compared with -45.83% for SPRO (price return, excluding dividends). Past performance does not predict future results.
Are Spero Therapeutics and Verrica Pharmaceuticals in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.