MetaCap

Alpha Teknova (TKNO) vs Xeris Biopharma (XERS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Alpha Teknova (TKNO) has outperformed Xeris Biopharma (XERS) over the past year, gaining 58.9% versus a gain of 24.3%. Over five years, XERS leads with a +409.5% price change compared with -63.5% for TKNO. Xeris Biopharma is the larger company by market cap ($1.91 billion vs $478.4 million), about 4.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

TKNO+58.95%XERS+24.27%
+83%+7%-69%
Oct 8, 20251 yearOct 8, 2026
TKNO-66.33%XERS+387.56%
+412%+146%-119%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

TKNO versus XERS key metrics
MetricTKNOXERS
Share price$8.91$10.50
Market cap$478.36M$1.91B
1-day change+5.57%+2.99%
YTD return+122.11%+29.81%
1-year return+58.95%+24.27%
5-year return-63.46%+409.50%
Forward P/E—28.36
EPS (TTM)$-0.31$-0.10
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$291.85M
Revenue growth (YoY)—+43.72%
Net income (latest FY)—$554.00K
Gross margin—85.41%
Operating margin—8.53%
Net margin—0.19%
52-week high$9.48$11.33
52-week low$1.91$5.25
Distance from 52-week high-6.01%-7.37%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+1.01%+22.53%
Average volume232.69K2.17M
Shares outstanding53.69M182.32M
Employees158435
SectorHealth CareHealth Care
IndustryBiotechnology: In Vitro & In Vivo Diagnostic SubstancesBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Xeris Biopharma is about 4.0 times larger than Alpha Teknova by market value ($1.91B vs $478.36M).
  • TKNO has outperformed XERS by 34.7 percentage points over the past year.

About Alpha Teknova

TKNO stock →

Alpha Teknova, Inc. produces critical reagents for the discovery, development, and commercialization of novel therapies, vaccines, and molecular diagnostics in the United States and internationally.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 158 employees

About Xeris Biopharma

XERS stock →

Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome.

Health Care · Biotechnology: Pharmaceutical Preparations · 435 employees

TKNO vs XERS FAQ

Which is bigger, Alpha Teknova or Xeris Biopharma?

Xeris Biopharma (XERS) is larger, with a market capitalization of $1.91B compared with $478.36M for Alpha Teknova (TKNO).

Which stock has performed better over the past year, TKNO or XERS?

TKNO returned +58.95% over the past 12 months, compared with +24.27% for XERS (price return, excluding dividends). Past performance does not predict future results.

Are Alpha Teknova and Xeris Biopharma in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: In Vitro & In Vivo Diagnostic Substances for Alpha Teknova and Biotechnology: Pharmaceutical Preparations for Xeris Biopharma.

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